AAO
<ѻý class="page-description">American Academy of Ophthalmologyѻý>Significant improvement beyond 100 weeks after single injection of mutation-agnostic MCO-010
Office procedure reduced visual field loss by 29% over 6 years versus eye drops
Drug targeting junctional zone reduces GA growth by 48% in 3 months, oral agent moderately active
Study suggests potential to eliminate a third of in-office visits without harming care
Study adds leg and ankle fractures, intracranial hemorrhage to evidence on falls, hip fracture
History of injections tied to multiple postop complications, but data open to questioning
No change in visual acuity, office-visit interval almost doubled during 6 months
Significant decrease in rate of photoreceptor loss in two randomized trials
Consistent vision effect with complement C1q inhibitor, despite no effect on lesion size
Some degree of improvement in disease status in 70% of patients treated with tarcocimab
All but one patient with nonproliferative diabetic retinopathy had stable disease or improvement
Improved visual acuity, retinal thickness at 6 and 12 weeks, but treatment burden questioned
Other studies report fewer reoperations with combo eye surgery and vision risk with shingles
Tarcocimab noninferior to aflibercept while cutting treatment burden in half
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AAO: American Academy of Ophthalmology
October 2024
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ASRS: American Society of Retina Specialists
July 2024
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ASCRS: American Society of Cataract & Refractive Surgery
May 2023
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AAOPT: American Academy of Optometry
October 2017