SOHO
<ѻý class="page-description">Society of Hematologic Oncologyѻý>Response rate exceeds 60%, with 15- to 20-month duration with epcoritamab
One of 40 patients changed treatment but all remained on brentuximab regardless of scan results
Molecular or cytogenetic response at 3 months correlated with better survival
Newer therapies and strategies might show more promise for boosting survival
Treatment with "pediatric-inspired protocols" improved event-free, relapse-free survival
Risk of relapse was also lower in the group who received the cell therapy
Good response rate with camidanlumab tesirine, although a lot of patients experienced AEs
Belamaf plus lenalidomide-dexamethasone achieved encouraging responses
Strategy applied in OPTIC trial may mitigate adverse events without sacrificing benefit
About a third of patients, including those with TP53 mutations, achieved complete remission
Emphasis on novel biological approaches in treating patients with hematologic malignancies
Rational combinations, new targets, and a first-ever phase III trial with a survival endpoint
Also at SOHO: Ponatinib proves mettle in pretreated CML
Objective responses in a majority of patients
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ASTRO: American Society for Radiation Oncology
September 2024
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ESMO: European Society for Medical Oncology
September 2024
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ASCO: American Society of Clinical Oncology
May 2024
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AACR: American Association for Cancer Research
April 2024