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Osteoporosis

News, opinions and meeting coverage in endocrinology.

FDA APPROVED Interchangeable biosimilars to Prolia and Xgeva over a computer rendering of bone affected by osteoporosis.

<乌鸦传媒>FDA OKs First Interchangeable Biosimilars for Denosumab

New products will carry all the same indications as Prolia and Xgeva, though launch date unclear

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Amy Schumer's Cushing's Dx; One Billion People With Obesity; Vitamin D for T1D

News and commentary from the endocrinology world

AAOS over a photo of Moscone Center in San Francisco, CA

<乌鸦传媒>Clear Opportunity to Identify Patients With Osteoporosis Commonly Missed

Hip surgeons could, but mostly don't, send at-risk patients for screening

A photo of a Prolia auto injector

<乌鸦传媒>Denosumab Protective Against Diabetes?

Study found lower diabetes incidence with osteoporosis drug for patients who stayed on treatment

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Insulin Discontinuation Tension; FDA OKs Osteopenia Belt; Limited Mounjaro Supply

News and commentary from the endocrinology world

A photo of a senior man walking on the beach in Australia

<乌鸦传媒>Adults Who Cite Walking Difficulty Face Higher Fracture Risk

Australian study suggests walking ability can help identify candidates for more assessment

A photo of the Prolia auto injector and packaging.

<乌鸦传媒>FDA Slaps Boxed Warning on Osteoporosis Drug

Denosumab can cause severe hypocalcemia in patients with advanced CKD, agency finds

A computer rendered cutaway of a spine affected by osteoporosis

<乌鸦传媒>Calcium Levels Quickly Become Critical for Many Denosumab-Treated Women on Dialysis

New findings led to boxed warning on drug's labeling for advanced CKD patients

A photo of a mature man with his arm in a sling sitting on a couch.

<乌鸦传媒>Fracture Risk Bumped With Testosterone Therapy in Hypogonadal Men

Researchers said this was not what they expected to find

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>T1D Trial Paused After Deaths; Mounjaro Not Just Cosmetic; Late-Stage Hot Flash Win

News and commentary from the endocrinology world

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Hibernating Squirrels for Obesity? Dialysis Warning; Endocrinology and Telehealth

News and commentary from the endocrinology world

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>New Diabetes Care Standards; Near 40% Ditch T2D Meds; Zepbound Hits Shelves

News and commentary from the endocrinology world

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Phase II Wins, Losses for Obesity Drugs; More Positive Veozah Data; Walking Off T2D

News and commentary from the endocrinology world

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Glucose Supplement Recalled; ADA Sued by Former Employee; Forteo Generic OK'd

News and commentary from the endocrinology world

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Farxiga Cuts A1c in Pediatric Diabetes; Late-Stage CAH Win; At-Home Menopause Test

News and commentary from the endocrinology world

<乌鸦传媒>Inflammation of the Aorta; Afib in the Hospital

Also in TTHealthWatch: standards for osteoporosis screening and HbA1c in premenopausal women

$An x-ray image of an intertrochanteric fracture of the left femur$

<乌鸦传媒>Postmenopausal Fracture Risk for SGLT2 Inhibitors Similar to Other Diabetes Drugs

Lower risk compared with DPP-4 inhibitors, and聽similar risk versus GLP-1 receptor agonists

ENDO over a photo of McCormick Place West in Chicago, IL.

<乌鸦传媒>ENDO 2023 Roundup: More Imcivree Data; Statement on Aging; Novel Hypoparathyroid Tx

Some more highlights from the Endocrine Society's annual meeting

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Oral Semaglutide Sheds Pounds; USPSTF Taking Obesity Comments; Plant Extract for T2D

News and commentary from the endocrinology world

AACE over a photo of the San Diego Convention Center in San Diego, CA.

<乌鸦传媒>Novel Hormone Replacer Holds Up Long-Term for Hypoparathyroidism

But drug remains in regulatory limbo

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>New Reader for FreeStyle Libre 3; COVID Bumps Diabetes Risk; Tepezza Label Expanded

News and commentary from the endocrinology world

A photo of a bone density scan

<乌鸦传媒>Osteoporosis: Another Dementia Predictor?

Low bone mineral density in certain places linked with dementia onset

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Dexcom G7 CGM Covered by Medicare; T1D Off-Label Drug Use; Another Tepezza Lawsuit

News and commentary from the endocrinology world

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>Rybelsus Now OK'd in First Line; Menopause Before Transition; Novel T2D Drug Flops

News and commentary from the endocrinology world

A photo of a woman holding a glass of water and a vitamin D supplement in her palm.

<乌鸦传媒>Higher BMI May Blunt Effects of Vitamin D Supplementation

In VITAL study, lower increases in total 25-OHD levels seen for those with greater body weight

Endo Break over a computer rendering of a man with illustrated body organs.

<乌鸦传媒>New Hypercalcemia Guideline; Untreated Hyperparathyroidism Risky; PFAS Phase-Out

News and commentary from the endocrinology world

A kidney patient receives treatment at a hospital.

<乌鸦传媒>Watch for Severe Hypocalcemia in Dialysis Patients on Prolia, FDA Warns

Agency said potential risk may require more frequent blood calcium monitoring

ASBMR over a photo of the Austin Convention Center in Austin, Texas

<乌鸦传媒>One-Two Punch of Romosozumab, Denosumab Improved BMD and Reduced Fractures

Taking the bone-forming agent followed by the antiresorptive was better than denosumab alone

ASBMR over a photo of the Austin Convention Center in Austin, Texas

<乌鸦传媒>Novel Agent Hints at Bone Growth Boost Without Hematopoietic Risks

Phase I study shows ability to modulate cell signaling

ASBMR over a photo of the Austin Convention Center in Austin, Texas

<乌鸦传媒>Denosumab Halts Bone Loss From Ovarian Suppression, AIs for Breast Cancer

Areal BMD increased when given at the start of maximal estradiol depletion therapy

ASBMR over a photo of the Austin Convention Center in Austin, Texas

<乌鸦传媒>Fish Oil Supplement Fails to Reduce Hip Fractures

Further bad news for omega-3 fatty acids in VITAL trial analysis

ASBMR over a photo of the Austin Convention Center in Austin, Texas

<乌鸦传媒>Cardiovascular Risks Not Increased With Denosumab

Large observational databases mitigate concerns about the osteoporosis therapy

ASBMR over a photo of the Austin Convention Center in Austin, Texas

<乌鸦传媒>Predicting Fractures in RA: Is FRAX Useful in the Modern Treatment Era?

Algorithm held its own, but not many study patients were on biologics

ASBMR over a photo of the Austin Convention Center in Austin, Texas

<乌鸦传媒>Good News, Bad News for Global Hip Fracture Rates

Incidence has declined, but burden will increase as older population grows

A computer rendering of different femur breakpoints.

<乌鸦传媒>More Hip Fractures Seen in Women With This Diet

Study compared vegetarian, pescatarian, and meat eaters

AACE over a photo of the Hilton San Diego Bayfront in San Diego, CA

<乌鸦传媒>Tymlos Boosts Bone Health in Men With Osteoporosis

Daily agent upped bone mineral density at multiple sites in phase III ATOM trial

A photo of a teen male cooking at home.

<乌鸦传媒>PFAS Exposure Linked to Weaker Bones in Teen Boys

Association not seen in female teens, though

A photo of a senior woman holding a glass of water and a white pill.

<乌鸦传媒>Could NSAIDs Negate Bisphosphonate Benefits?

Women taking clodronate and NSAIDs didn't see a protective effect

A photo of a female patient鈥檚 legs protruding from a CT scanner

<乌鸦传媒>Pricier, Questionable Bone Density Scan Growing in Use

QCT delivers far more radiation and exaggerates spinal bone loss, so why is it on the rise?

A photo of a print out of a bone mineral density scan.

<乌鸦传媒>Two Bone Scans Three Weeks Apart, Results in Reverse

Discordant QCT, DXA results confuse patients and doctors, "How can they both be right?"

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