<ѻý>Alzheimer's Risk Higher If Mom Had Memory Problemsѻý> Maternal history of memory impairment tied to higher amyloid burden Jun 17, 2024
<ѻý>A Single, Surprising Gene Behind a Disorder That Causes Intellectual Disabilityѻý> Researchers estimate the disorder may affect as many as one in 20,000 young people May 31, 2024
<ѻý>Hereditary Angioedema Attacks Reduced With Donidalorsen Prophylaxisѻý> Investigational treatment passes muster in phase III trial May 31, 2024
<ѻý>Lifestyle-Dementia Links Persist Regardless of Risk Genes, French Study Showsѻý> Dementia prevention efforts may be beneficial despite genetic susceptibility May 23, 2024
<ѻý>Fertility Treatment Safe for Breast Cancer Survivors With BRCA Mutationsѻý> No significant increased risk of recurrence or pregnancy complications May 17, 2024
<ѻý>Gene Editing Improves Vision in Rare and Devastating Retinal Disorderѻý> Therapy improved best corrected visual acuity in four of 14 patients, and others benefited too May 07, 2024
<ѻý>Alzheimer's Variant May Cause Distinct Form of the Diseaseѻý> Almost all APOE4 homozygotes develop Alzheimer's disease May 06, 2024
<ѻý>Impact of Recombinant Replacement Therapy Detailed in Genetic Clotting Disorderѻý> Trial that led to FDA approval shows a big difference in replacement levels versus usual care May 01, 2024
<ѻý>Age-Related Somatic Mutations Implicated in Cardiovascular Deathѻý> Clonal hematopoiesis a red flag for people with asymptomatic carotid atherosclerosis Apr 29, 2024
<ѻý>FDA Approves First Drug for WHIM Syndromeѻý> CXCR4 antagonist mavorixafor effectively boosts neutrophils and lymphocytes to reduce infections Apr 29, 2024
<ѻý>Genetics Studies Have a Diversity Problem That Researchers Struggle to Fixѻý> Most data based on DNA from white people, but small differences can have big health outcomes Apr 28, 2024
<ѻý>Newborn Screening for SMA Appears to Offer Functional Benefitsѻý> German cohort study suggests earlier initiation of treatment benefits sitting, walking Apr 08, 2024
<ѻý>Need 10,000 Daily Steps to Prevent Obesity? It May Depend on Geneticsѻý> Current recommendations may underestimate activity needs for people with high genetic risk Mar 27, 2024
<ѻý>Overdosing on Chemo: A Common Gene Test Could Save Hundreds of Lives Each Yearѻý> Treatment can be deadly for enzyme-deficient patients; NCCN doesn't call for preemptive testing Mar 26, 2024
<ѻý>FDA Approves New Frontline Regimen for Aggressive ALLѻý> Ponatinib lands indication in combination with chemo for Philadelphia chromosome-positive cases Mar 22, 2024
<ѻý>Spinal Delivery of Gene Therapy Promising for Neurodegenerative Diseaseѻý> Early-phase clinical trial was suggestive of slower progression of giant axonal neuropathy Mar 20, 2024
<ѻý>Mutation Linked to Increased Risk of Prostate Cancer Mortalityѻý> Cancer-specific mortality twice as high in patients with specific genotype for HSD3B1 allele Mar 20, 2024
<ѻý>Higher Polygenic Risk Score Tied to Increased Risk for Glaucomaѻý> Risk scores may allow action before irreversible damage occurs in those with ocular hypertension Mar 19, 2024
<ѻý>Cancer Prevention Strategies Linked to Mortality Reduction in BRCA Carriersѻý> Cohort studies indicate oophorectomy, breast MRI surveillance save lives, researchers say Feb 29, 2024
<ѻý>Oral Drug Gains Steam as On-Demand Option for Hereditary Angioedema Attacksѻý> Investigational sebetralstat offered symptom relief in under 2 hours Feb 28, 2024
<ѻý>Faster Cures, More Genetic Treatments: A Q&A With NIH's Joni Rutterѻý> The NCATS Biomedical Data Translator is giving researchers ideas for new disease therapies Feb 23, 2024
<ѻý>Potential Biomarker for Perforated Appendicitis Shows Link to Severe Sepsisѻý> Test that can differentiate between simple and perforated appendicitis is "highly desirable" Feb 20, 2024
<ѻý>Genome Sequencing Identified Variants in Fetal Structural Anomaliesѻý> Researcher touts identification of "high percentage of genetic disorders" Feb 14, 2024
<ѻý>A Clue on Why Lupus, Other Autoimmune Diseases Strike Far More Women Than Menѻý> New research shows that the extra X chromosome is involved, but in an unexpected way Feb 01, 2024
<ѻý>Novel Gene Therapy Allows Kids With Inherited Deafness to Hearѻý> "This is real proof showing gene therapy is working," says researcher Jan 25, 2024
<ѻý>MS Risk Linked to Ancient Migrationsѻý> Findings may help demystify multiple sclerosis Jan 10, 2024
<ѻý>FDA Approves New Agent for Nerve Pain From Rare Inherited Diseaseѻý> Eplontersen gets a nod for polyneuropathy from hereditary transthyretin-mediated amyloidosis Dec 22, 2023
<ѻý>Pomalidomide Cuts Severe Epistaxis in Genetic Bleeding Disorderѻý> 24 weeks of daily treatment significantly reduced recurrent nosebleeds in HHT trial Dec 13, 2023
<ѻý>Why Is VEXAS Syndrome Often Fatal? Here's an Answerѻý> New study suggests immunodeficiency is a previously unrecognized feature Dec 12, 2023
<ѻý>A Closer Look at the Approval of CRISPR/Cas9 Gene Therapy for Sickle Cell Diseaseѻý> This landmark event brings up broader considerations and implications for other diseases Dec 11, 2023
<ѻý>Antisense Drug Trial Provides Key Insights About Huntington's Diseaseѻý> Lessons learned from investigational tominersen Dec 06, 2023
<ѻý>Jamie Foxx's Health Scare; 23andMe Hacked; Decongestant Probe Announcedѻý> Health news and commentary from around the Web gathered by ѻý staff Dec 05, 2023
<ѻý>Here's Why People Think They Developed Food Allergiesѻý> Survey finds that 13% thought genetics were responsible, 27% blamed eating behaviors Nov 16, 2023
<ѻý>Promising Debut for CRISPR Gene Editing Therapy for LDL Loweringѻý> Preliminary data support concept of "molecular surgery" on PCSK9 gene Nov 12, 2023
<ѻý>Zoonotic Spillovers; DNA and RNA Testing for Cancer Riskѻý> Also in TTHealthWatch: genes and health conditions among Icelanders Nov 11, 2023 podcast
<ѻý>First Treatment Approved for Genetic Clotting Disorderѻý> Adzynma indicated as prophylactic or on-demand enzyme replacement therapy in cTTP Nov 10, 2023
<ѻý>Potential Cure for Sickle Cell Clears Hurdle for Approvalѻý> FDA advisors suggest the benefits of gene therapy outweigh risks of off-target editing Oct 31, 2023
<ѻý>Quick Genetic Test Offers Hope for Sick, Undiagnosed Kids, but Few Insurers Cover Itѻý> Test can "change the trajectory of these children's diseases" Oct 29, 2023
<ѻý>FDA Turns Down ATTR Cardiomyopathy Drugѻý> Decision cites insufficient evidence of clinical meaningfulness Oct 09, 2023
<ѻý>In BRCA Breast Cancer, Prophylactic Salpingo-Oophorectomy Tied to Better Survivalѻý> PSO should be performed early, particularly for those with the BRCA1 variant, researchers say Oct 04, 2023