乌鸦传媒

<乌鸦传媒 class='mpt-top_cat_title'>Oncology/Hematology >

Hematology

News, opinions and meeting coverage in oncology/hematology.

ASH over a photo of San Diego Convention Center.

<乌鸦传媒>Lovo-Cel 'Life-Changing, Transformative' in Sickle Cell Disease

Near complete resolution of pain events in patients, including adolescents

<乌鸦传媒>AI and Breast Cancer Screening; Cancer After Treatment for Sickle Cell

Also in TTHealthWatch: mail-in cervical cancer screening kits

FDA APPROVED exagamglogene autotemcel (Casgevy) and lovotibeglogene autotemcel (Lyfgenia) over an image of a sickle cell.

<乌鸦传媒>Milestone Gene Therapies for Sickle Cell Disease Greenlit by FDA

Casgevy and Lyfgenia approved for one-time treatment of sickle cell disease

A photo of a pink rubber gloved hand hanging bags of donated blood

<乌鸦传媒>Doing More With Less Blood

Blood management programs can save money and resources

FDA APPROVED iptacopan (Fabhalta) over a computer rendering of damaged red blood cells.

<乌鸦传媒>FDA Approves Oral Factor B Inhibitor for Paroxysmal Nocturnal Hemoglobinuria

Iptacopan tops C5 Inhibitors for sustained hemoglobin levels, eliminating need for transfusion

A computer rendering of non-Hodgkin lymphoma cells in the blood flow

<乌鸦传媒>Rituximab Maintenance Boosts Survival for Older Adults With MRD-Negative MCL

Patients with treatment-sensitive disease may benefit most from continued treatment, says expert

A photo of a female nurse holding a bag of blood.

<乌鸦传媒>Novel Therapy Reduced Transfusion Dependence in Lower-Risk MDS

40% of patients treated with imetelstat were transfusion-free for at least 8 weeks

FDA APPROVED pirtobrutinib (Jaypirca) over a computer rendering of chronic lymphocytic leukemia cells.

<乌鸦传媒>Non-Covalent BTK Inhibitor Approved for CLL

Response rates with pirtobrutinib reached 72% in heavily pretreated patient population

YIR FOLLICULAR LYMPHOMA over a microscope image of follicular lymphoma.

<乌鸦传媒>Year in Review: Follicular Lymphoma

A promising year for bispecific antibodies

A scanning electron microscope image of CAR-T cells attacking a cancer cell.

<乌鸦传媒>FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy

Applies to all approved therapies, but benefits still outweigh risks, agency says

A photo of a spilled bottle of Eliquis tablets.

<乌鸦传媒>Apixaban Prophylaxis Fails to Reduce Clots in Pediatric ALL

However, it may benefit children at increased risk of thrombosis

A photo a male doctor and female nurse looking at a laptop while a nurse hangs an IV bag over a senior patient in a hospital.

<乌鸦传媒>Alteplase Not Harmful in NOAC Users, Even in a More Bleeding-Prone Cohort

No excess brain bleeds in an Asian population receiving lytic therapy for stroke

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

<乌鸦传媒>Opioid Doc Sentenced; World's First Sickle Cell Gene Tx; FTC Warns Diet Influencers

Health news and commentary from around the Web gathered by 乌鸦传媒 staff

FDA ADCOMM pralatrexate (Folotyn), belinostat (Beleodaq) over a computer rendering of lymphoma cells in the blood flow.

<乌鸦传媒>FDA Panel: Tolerating Approval Outliers Would Set 'Dangerous Precedent'

No easy answers for two drugs for rare lymphoma on long cruise with accelerated approval

FDA ADCOMM taurolidine + heparin catheter lock solution (Defencath) over a photo of a man receiving dialysis.

<乌鸦传媒>FDA OKs Product to Thwart Bloodstream Infections During Dialysis

Taurolidine-heparin solution reduced infections by 71% versus heparin alone

A photo of the vial and packaging of Aliqopa.

<乌鸦传媒>Lymphoma Drug Copanlisib to Be Pulled From U.S. Market

Failed confirmatory trial takes down another PI3K inhibitor

FDA APPROVED ADAMTS13, recombinant-krhn (Adzynma) over a computer rendering of a blood clot.

<乌鸦传媒>First Treatment Approved for Genetic Clotting Disorder

Adzynma indicated as prophylactic or on-demand enzyme replacement therapy in cTTP

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>Vitamin D for Neuropathy; Good & Bad News for CAR-T; New Labeling for Surgical Mesh

News, features, and commentary about cancer-related issues

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>Wearables as Cancer Monitors; No China Price Break; Cancer Mystery in Appalachia

News, features, and commentary about cancer-related issues

FDA ADCOMM exagamglogene autotemcel (exa-cel) over a computer rendering of sickle cells in the bloodstream.

<乌鸦传媒>Potential Cure for Sickle Cell Clears Hurdle for Approval

FDA advisors suggest the benefits of gene therapy outweigh risks of off-target editing

FDA ADCOMM exagamglogene autotemcel (exa-cel) over a computer rendering of sickle cells in the bloodstream.

<乌鸦传媒>FDA Reviewers Question Safety of Sickle Cell Gene Therapy

Efficacy results "strongly positive," but unintended off-target effects a question

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>Soap to Fight Skin Cancer; $1,000 Early Cancer Detection Test; FDA Approval in MDS

News, features, and commentary about cancer-related issues

A computer rendering of multiple myeloma cells in the bloodstream.

<乌鸦传媒>Quad Regimen for High-Risk Myeloma Produces High Rates of Durable MRD Negativity

Two-thirds of transplant-eligible patients met endpoint with isatuximab/KRd

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>Lonely Cancer Deaths; Virtual Reality for Pain; 3D Models May Improve Treatment

News, features, and commentary about cancer-related issues

A photo of a box of Hemlibra for injection over a computer rendering of red blood cells.

<乌鸦传媒>Emicizumab Can Delay Immunosuppressive Tx in Acquired Hemophilia A

"Strategy will probably be practice-changing," says expert

ASA over a photo of the Moscone Center in San Francisco, California.

<乌鸦传媒>Hemoglobin Targets a Good Idea for Massively Transfused Patients

Outcomes improved with values approaching 10 g/dL

A computer rendering of a ruptured artery.

<乌鸦传媒>Cryoprecipitate, REBOA Flop for Improving Major Hemorrhage Outcomes

The first randomized trials of both approaches failed

CHEST over a photo of the Hilton Hawaiian Village Waikiki Beach Resort in Honolulu, HI.

<乌鸦传媒>Rare Lung Bleeds Cluster in DOAC Users, Implications Unclear

Pattern found in diffuse alveolar hemorrhage reports in FAERS

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>Chemo Shortage: 'Paycheck to Paycheck'; Cancer Blood Test Shines; Struggling to Live

News, features, and commentary about cancer-related issues

A photo of Richard Baron.

<乌鸦传媒>ABIM CEO Retirement Comes Amid Wave of Criticism

Richard Baron, MD, plans to step down as pushback against MOC grows

A photo of boxes of immunoglobulin intravenous.

<乌鸦传媒>IV Immunoglobulin May Cut Infection Risk of Anti-BCMA Agents for Myeloma

Small retrospective study finds fewer severe infections during periods of replacement therapy

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>Cancer Drug Shortages for Kids; Pharma Agrees to Price Talks; Catch-Up on Screening

News, features, and commentary about cancer-related issues

Photos of the box of Zelboraf tablets and the vial of Gazyva over a computer rendering of hairy cell leukemia

<乌鸦传媒>Frontline Combo Yields High Remission Rate in Hairy Cell Leukemia

And almost all complete responders in small trial achieved MRD negativity

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>TikTok Dinged for Misinformation; BRCA Risk Overestimated; Cheers for Oncology

News, features, and commentary about cancer-related issues

A computer rendering of a blood clot.

<乌鸦传媒>Another Win for Biomarker-Driven Thromboprophylaxis for Patients With Cancer

Threefold risk reduction with enoxaparin in high-risk gastrointestinal, lung cancers

FDA APPROVED momelotinib (Ojjaara) over a computer rendering of myelofibrosis cells.

<乌鸦传媒>FDA Approves JAK Inhibitor That Addresses Anemia in Myelofibrosis

In a phase III trial, momelotinib reduced anemia, constitutional symptoms, and splenomegaly

A photo of a surgeon performing radiofrequency ablation

<乌鸦传媒>Weight-Loss Surgery Tied to Lower Blood Cancer Risk in Women

Consider surgery for primary prevention in people with obesity, researchers suggest

Onco Break over a computer rendering of a cancer cell.

<乌鸦传媒>Cisplatin Shortage Eases; Air Pollution Linked to Breast Cancer; Pap Test Confusion

News, features, and commentary about cancer-related issues

FDA APPROVED motixafortide (Aphexda) for use with filgrastim (Neupogen) over a fluorescent image of human stem cells

<乌鸦传媒>Stem-Cell Mobilization Booster Wins FDA Approval for Multiple Myeloma

Motixafortide plus filgrastim increased adequate harvest rate from 9.5% to 67.5%

SOHO over a photo of George R. Brown Convention Center in Houston, Texas.

<乌鸦传媒>FLT3 Inhibitor Improves AML Survival With or Without Stem-Cell Transplant

Best outcomes with transplantation, but non-transplant patients also benefited from quizartinib

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