<ѻý>Dear Blood Donors, You've Given Me the Gift of Lifeѻý> I offer my gratitude through acceptance, acknowledgement, and reflection Feb 06, 2022
<ѻý>FDA Concerned About Safety of Lymphoma Drugѻý> Hint of excess mortality in trial of umbralisib/ublituximab prompts public notice Feb 03, 2022
<ѻý>Finally, a 'New Standard' for Severe Aplastic Anemiaѻý> After 3 decades of failures, RACE trial shows superiority of new first-line regimen Jan 05, 2022
<ѻý>Myeloma at Younger Age Shortens Lifespan Despite Lengthy Overall Survivalѻý> Disease characteristics, prognostic factors similar to those of older patients Jan 04, 2022
<ѻý>Targeted Agent Improves Survival in FLT3-Positive Acute Myeloid Leukemiaѻý> OS, EFS improved versus historical controls with addition of midostaurin to chemotherapy Dec 17, 2021
<ѻý>Another Study Reinforces Chemo-Free Therapy for Newly Diagnosed CLLѻý> Ibrutinib-rituximab extends PFS versus chemoimmunotherapy, especially in unmutated disease Dec 16, 2021
<ѻý>Less Is More: Rituximab Retreatment Tops Maintenance for Follicular Lymphomaѻý> Updated analysis confirms advantages of less aggressive approach to low-burden disease Dec 16, 2021
<ѻý>Gene Therapy Resolves Severe Pain Events in Sickle Cell Diseaseѻý> LentiGlobin also normalized hemoglobin and reduced hemolysis markers Dec 15, 2021
<ѻý>Can Dasatinib Dose Be Halved in Low-Risk CML?ѻý> Lower dose associated with improved tolerability, similar responses in propensity score analysis Dec 14, 2021
<ѻý>CAR T-Cell Win Streak Stopped by Negative Trial in Aggressive LBCLѻý> Patients, trial design, logistics among possible explanations for lack of EFS benefit Dec 14, 2021
<ѻý>Fitusiran Prophylaxis Cuts Bleeding in Hemophilia A/Bѻý> Monthly infusion vs on-demand bypassing agents effective in patients with or without inhibitors Dec 14, 2021
<ѻý>R-CHOP Toppled in First-Line DLBCL Trialѻý> Replacing vincristine with polatuzumab vedotin improved PFS, without adding toxicity Dec 14, 2021
<ѻý>Gentler Regimen Leads to High Response Rate in Older Patients With B-Cell ALLѻý> One-year OS rate of 78% with fractionated inotuzumab ozogamicin exceeds 60% historical rate Dec 13, 2021
<ѻý>β-Thalassemia Patients Go Transfusion-Free With Gene Therapyѻý> Treatment with beti-cel is "potentially curative" in this transfusion-dependent group Dec 13, 2021
<ѻý>R2 Maintenance for Elderly MCL Patients Worth the Risk?ѻý> Longer PFS with addition of lenalidomide to rituximab, but also more toxicity Dec 13, 2021
<ѻý>Venetoclax Regimens for 'Fit' CLL Yield High Undetectable MRD Ratesѻý> Combined with obinutuzumab, plus or minus ibrutinib, outperforms chemoimmunotherapy Dec 13, 2021
<ѻý>CAR T-Cell Therapy Makes Strong Case for Earlier Use in Lymphomaѻý> Large increases in event-free survival with two CAR T-cell products in second line Dec 11, 2021
<ѻý>Next-Gen MRD Testing Predicts Acute Leukemia Relapse After CAR-Tѻý> Nearly all patients with detectable disease relapsed or progressed to transplant, other therapies Dec 01, 2021
<ѻý>Chemo-Free Regimen Highly Active in Older Mantle Cell Lymphoma Patientsѻý> Overall response rate of 96% with ibrutinib-rituximab, but cardiotoxicity a possible issue Nov 29, 2021
<ѻý>Novel Triplet Yields Undetectable MRD Status in 90% of CLL/SLL Patientsѻý> Zanubrutinib plus obinutuzumab and venetoclax was also well tolerated Nov 29, 2021
<ѻý>Pegylated Interferon Wins FDA Approval for Polycythemia Veraѻý> Majority of patients attained complete hematologic response with ropeginterferon alfa-2b Nov 15, 2021
<ѻý>Is Multiple Myeloma a Greater Threat to Black Patients?ѻý> Incidence and treatment disparities combined with a heightened COVID risk is cause for concern Nov 11, 2021
<ѻý>A Gentler Standard for Acute Promyelocytic Leukemia in Kidsѻý> ATRA/arsenic trioxide without maintenance therapy resulted in 99-100% survival at 2 years Nov 11, 2021
<ѻý>Vaccinated Blood Cancer Patients Still at Risk for Severe COVID-19ѻý> Those with hematologic malignancies also remain at higher risk of mortality as well Nov 08, 2021
<ѻý>Ibrutinib Boosts Survival in Younger Patients With Certain DLBCL Subtypesѻý> New analysis "casts the PHOENIX trial in a new light," authors say Nov 04, 2021
<ѻý>FDA Approves STAMP Inhibitor for Chronic Myeloid Leukemiaѻý> Patients treated with two or more TKIs and those with T315I mutation gain new option Nov 01, 2021
<ѻý>Ibrutinib-Rituximab Wins Out in Waldenstrom's Macroglobulinemiaѻý> Risk of disease progression or death reduced by 75% versus rituximab alone Oct 11, 2021
<ѻý>Longer Hydroxyurea Tied to Improved Sickle-Cell Heart Issuesѻý> Kids on treatment for less than 1 year had a significantly greater prevalence of LV dilation Sep 16, 2021
<ѻý>9/11 Responders Face Higher Risk of Multiple Cancersѻý> Longer follow-up sheds light on the long-term consequences of exposure to disaster site Sep 10, 2021
<ѻý>Life Expectancy Still Lower for Blood or Marrow Transplant Recipientsѻý> Although late mortality has decreased over the past 40 years Sep 09, 2021
<ѻý>Liver Toxicity in Gene Therapy Trials Could Merit Stricter Entry Criteriaѻý> FDA panel weighs in on lower vector doses and role of animal studies Sep 03, 2021
<ѻý>Adding Mycophenolate Mofetil Improves Outcomes in ITPѻý> "Somewhat decreased" quality of life, however, British study finds Sep 01, 2021
<ѻý>Non-Chemo Regimen Highly Active in R/R Hodgkin Lymphomaѻý> Three-year progression-free survival of 77%, including 91% after stem-cell transplantation Aug 23, 2021
<ѻý>Are Hemoglobin Cutoffs for Anemia Outdated?ѻý> A growing call for WHO criteria to be tightened Aug 06, 2021
<ѻý>Woman Develops Tiny Blood Spots on Her Body After COVID Shotѻý> Case highlights need for quick diagnosis and management of rare disorder Aug 05, 2021
<ѻý>Anti-CD7 CAR-T Therapy Yields High Response Rate in Acute Leukemiaѻý> Complete responses in 18 of 20 patients with relapsed/refractory T-cell ALL Aug 04, 2021
<ѻý>Add-On Venetoclax Promising in Younger, Fit AML Patientsѻý> "Safe and feasible intensive regimen" in small single-center study Jul 30, 2021
<ѻý>Call in the T-Cell Cavalry to Fight COVID in the Immunocompromisedѻý> Preliminary research suggests immunotherapy could play role in protecting vaccine non-responders Jul 29, 2021
<ѻý>Shingrix OK'd for Immunocompromised Adultsѻý> CDC's vaccine committee currently discussing vaccine for this population, manufacturer says Jul 26, 2021
<ѻý>Keytruda Before, After Surgery Improves Outcome in TNBCѻý> Results from KEYNOTE-522 show "practice-changing" impact on EFS Jul 15, 2021