<ѻý>When a Revolutionary Cancer Treatment Causes Cancerѻý> The potential benefits of CAR T-cell therapies still far outweigh the risks Jan 27, 2024
<ѻý>CAR-T Investigation: FDA Leaders Detail Decision on Cancer Risk Warningѻý> Post-treatment cases grow to 22 since products' initial approvals Jan 24, 2024
<ѻý>FDA Calls for New Boxed Warning on All CAR-T Productsѻý> Most serious warning would alert patients, providers on potential risk for secondary malignancies Jan 23, 2024
<ѻý>Two Million Cancers; Casgevy OK'd for Thalassemia; Rectal Exams and Prostate Cancerѻý> News, features, and commentary about cancer-related issues Jan 19, 2024
<ѻý>Carvedilol No Help in Preventing Heart Failure in Childhood Cancer Survivorsѻý> While safe, the results do not support use of the drug in anthracycline-exposed survivors Jan 10, 2024
<ѻý>Menin Inhibitor Yields 63% ORR in Heavily Pretreated Acute Leukemiaѻý> Investigational drug revumenib now under review at FDA for KMT2A-rearranged disease Dec 12, 2023
<ѻý>MRD Tied to Allo-Transplant Benefit in NPM1-Mutated Acute Myeloid Leukemiaѻý> No advantage for MRD-negative patients in first remission after induction, regardless of FLT3 ITD Dec 11, 2023
<ѻý>Frontline Venetoclax-Ibrutinib for CLL Boosts Survival in Fit Patientsѻý> Time-limited approach based on MRD response outperforms FCR, but U.S. applicability unclear Dec 10, 2023
<ѻý>Completely Oral Regimen Effective, Feasible in APLѻý> 97% of patients alive and relapse-free at 3 years Dec 10, 2023
<ѻý>Non-Covalent BTK Inhibitor Approved for CLLѻý> Response rates with pirtobrutinib reached 72% in heavily pretreated patient population Dec 04, 2023
<ѻý>Charting the Course: From Young Adult Leukemia Patient to Oncologistѻý> My experience shaped how I care for patients today Dec 03, 2023
<ѻý>FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapyѻý> Applies to all approved therapies, but benefits still outweigh risks, agency says Nov 28, 2023
<ѻý>Apixaban Prophylaxis Fails to Reduce Clots in Pediatric ALLѻý> However, it may benefit children at increased risk of thrombosis Nov 20, 2023
<ѻý>Wearables as Cancer Monitors; No China Price Break; Cancer Mystery in Appalachiaѻý> News, features, and commentary about cancer-related issues Nov 03, 2023
<ѻý>Soap to Fight Skin Cancer; $1,000 Early Cancer Detection Test; FDA Approval in MDSѻý> News, features, and commentary about cancer-related issues Oct 27, 2023
<ѻý>Lonely Cancer Deaths; Virtual Reality for Pain; 3D Models May Improve Treatmentѻý> News, features, and commentary about cancer-related issues Oct 19, 2023
<ѻý>Chemo Shortage: 'Paycheck to Paycheck'; Cancer Blood Test Shines; Struggling to Liveѻý> News, features, and commentary about cancer-related issues Oct 06, 2023
<ѻý>Cancer Drug Shortages for Kids; Pharma Agrees to Price Talks; Catch-Up on Screeningѻý> News, features, and commentary about cancer-related issues Sep 28, 2023
<ѻý>Frontline Combo Yields High Remission Rate in Hairy Cell Leukemiaѻý> And almost all complete responders in small trial achieved MRD negativity Sep 25, 2023
<ѻý>FLT3 Inhibitor Improves AML Survival With or Without Stem-Cell Transplantѻý> Best outcomes with transplantation, but non-transplant patients also benefited from quizartinib Sep 11, 2023
<ѻý>Early Major Response to Ponatinib in Pretreated CML Portends Better Outcomesѻý> Molecular or cytogenetic response at 3 months correlated with better survival Sep 08, 2023
<ѻý>Intensive Pretransplant Consolidation in Older AML Fails to Improve Resultsѻý> Newer therapies and strategies might show more promise for boosting survival Sep 07, 2023
<ѻý>Microdevices for Glioma; Cervical Adenocarcinoma Test; Language Gaps and Cancer Careѻý> News, features, and commentary about cancer-related issues Sep 07, 2023
<ѻý>More Intense ALL Therapy Improves Outcomes in Adolescents, Young Adultsѻý> Treatment with "pediatric-inspired protocols" improved event-free, relapse-free survival Sep 07, 2023
<ѻý>Non-Covalent BTK Inhibitor Yields High Response Rate in Pretreated CLLѻý> 73% of patients with prior exposure to covalent BTK inhibitors responded Jul 05, 2023
<ѻý>WHO Links Sweetener to Cancer; Younger-Age CRC Risk; PCOS and Ovarian Cancerѻý> News, features, and commentary about cancer-related issues Jun 29, 2023
<ѻý>No OS Benefit With Ibrutinib in Early-Stage, High-Risk CLLѻý> Study suggests "watch and wait" should remain standard of care Jun 28, 2023
<ѻý>Earlier Detection of Cardiac Dysfunction Possible for Young Adult Cancer Survivorsѻý> A case for monitoring global longitudinal strain despite normal LVEF Jun 20, 2023
<ѻý>Pushback on Price Negotiation; Genetic Testing Lags; More Foreign Help for Shortagesѻý> News, features, and commentary about cancer-related issues Jun 15, 2023
<ѻý>Base-Edited CAR-T Product 'Potent' in Relapsed Childhood T-Cell ALLѻý> One young patient achieved molecular remission within 28 days of infusion Jun 14, 2023
<ѻý>CAR-T for Chronic Lymphocytic Leukemia Hits Goal of Mid-Stage Trialѻý> All patients had progressed on BTK inhibitors and most had failed venetoclax Jun 12, 2023
<ѻý>Cross-Border Collaboration Improves Survival in Pediatric Leukemia Patientsѻý> 5-year OS increased to 100% in standard-risk ALL patients at a Tijuana hospital May 25, 2023
<ѻý>Adding Mylotarg to Chemo Fails to Boost Survival in NPM1-Mutated AMLѻý> But trial detects "meaningful benefit" when it comes to relapse, editorialists say May 15, 2023
<ѻý>FLT3 Inhibitor Doubles Overall Survival in Acute Myeloid Leukemiaѻý> Median OS improved from 15 months to nearly 32 months with quizartinib May 09, 2023
<ѻý>Blinatumomab Plus Chemo Effective in Aggressive Infant ALLѻý> Low incidence of relapse after treatment "remarkable," researchers say Apr 26, 2023
<ѻý>Targeted Agents Go Head-to-Head for Newly Diagnosed Ph+ ALLѻý> Trial crowns a winner, but how relevant is it amid the changing therapeutic landscape for ALL? Feb 16, 2023
<ѻý>The 'Extreme' Story of How Two Game-Changing Cancer Drugs Came to Marketѻý> New book by former Forbes senior editor pulls back the curtain on drug development Feb 13, 2023
<ѻý>Off-the-Shelf T-Cell Therapy Effective Against Viral Infections After Allo-HCTѻý> Produced an antiviral response in 95% of patients with six different types of infection Jan 13, 2023
<ѻý>Zanubrutinib Shows Good Tolerance in BTK-Inhibitor Intolerant Malignanciesѻý> Most patients had no recurrence of their original intolerance event Jan 10, 2023
<ѻý>Crystal Ball Cloudy for PI3K Inhibitors' Future in Hematologyѻý> After a year of negative news, some caution about throwing out the baby with the bath water Jan 02, 2023