<ѻý>Reprogramming Tumors; Bad Stool Samples; Human Experiences in Cancer Careѻý> News, features, and commentary about cancer-related issues Nov 17, 2023
<ѻý>First AKT Inhibitor Approved for Advanced Breast Cancerѻý> Capivasertib plus fulvestrant doubled progression-free survival versus fulvestrant-placebo Nov 17, 2023
<ѻý>Opioid Doc Sentenced; World's First Sickle Cell Gene Tx; FTC Warns Diet Influencersѻý> Health news and commentary from around the Web gathered by ѻý staff Nov 17, 2023
<ѻý>FDA Panel: Tolerating Approval Outliers Would Set 'Dangerous Precedent'ѻý> No easy answers for two drugs for rare lymphoma on long cruise with accelerated approval Nov 16, 2023
<ѻý>ASTRO Updates Guidelines on Partial Breast Irradiation for Early Invasive Cancerѻý> Evidence from RCTs indicates "oncologic equivalence" between partial and whole-breast irradiation Nov 16, 2023
<ѻý>FDA OKs New Option for Advanced ROS1-Positive Lung Cancerѻý> Drug achieved high response rates in TKI-naive and TKI-pretreated patients Nov 16, 2023
<ѻý>'We're Not There Yet': CAR T-Cell Therapy for Renal Cell Carcinomaѻý> Potential standard of care after current therapies, but key obstacles remain in the way Nov 15, 2023
<ѻý>FDA OKs Product to Thwart Bloodstream Infections During Dialysisѻý> Taurolidine-heparin solution reduced infections by 71% versus heparin alone Nov 15, 2023
<ѻý>Targeting New Pathways to Improve Outcomes in Renal Cell Carcinomaѻý> Building on recent success requires intervention at multiple steps in the cancer immunity cycle Nov 14, 2023
<ѻý>Lymphoma Drug Copanlisib to Be Pulled From U.S. Marketѻý> Failed confirmatory trial takes down another PI3K inhibitor Nov 14, 2023
<ѻý>Diabetes Linked to Higher Colorectal Cancer Riskѻý> Associated risks highest in those with recent diagnoses Nov 14, 2023
<ѻý>No Boost in Outcomes for Clear Cell RCC With Higher Belzutifan Doseѻý> A quarter of patients responded whether at the recommended or higher dose Nov 13, 2023
<ѻý>Pancreatic Cancer Doesn't Have to Be a Death Sentenceѻý> Early detection is the key to increasing survival rates Nov 13, 2023
<ѻý>Tyrosine Kinase Inhibitor Active in Heavily Treated Renal Cell Carcinomaѻý> Responses to "special drug" zanzalintinib in cabozantinib-exposed and unexposed patients Nov 11, 2023
<ѻý>Zoonotic Spillovers; DNA and RNA Testing for Cancer Riskѻý> Also in TTHealthWatch: genes and health conditions among Icelanders Nov 11, 2023 podcast
<ѻý>First Treatment Approved for Genetic Clotting Disorderѻý> Adzynma indicated as prophylactic or on-demand enzyme replacement therapy in cTTP Nov 10, 2023
<ѻý>Vitamin D for Neuropathy; Good & Bad News for CAR-T; New Labeling for Surgical Meshѻý> News, features, and commentary about cancer-related issues Nov 10, 2023
<ѻý>Bispecific Antibody Shows Clinical Activity in Recurrent Ovarian Cancerѻý> Alone or combined with a PD-1 inhibitor, ubamatamab showed promise in phase I trial Nov 09, 2023
<ѻý>Moving Beyond the 'Angelina Jolie Effect' to Address Cancer Disparitiesѻý> A "local heroes effect" can better reach communities of color Nov 09, 2023
<ѻý>New Oral Drug Approved for Metastatic Colorectal Cancerѻý> In phase III trials of pretreated patients, fruquintinib improved survival versus placebo Nov 09, 2023
<ѻý>Novel Therapies Show Early Promise in Advanced Gastroesophageal Cancersѻý> Results look good, but more data needed Nov 08, 2023
<ѻý>Senate Confirms Monica Bertagnolli as Next NIH Directorѻý> Vote was 62-36 in favor of the current National Cancer Institute director Nov 07, 2023
<ѻý>FDA Panel Backs High-Risk Designation for Salvaged Blood Irradiatorsѻý> With Class III designation, sponsors would have to prove safety, efficacy with randomized trials Nov 07, 2023
<ѻý>T-DXd Tied to Encouraging Survival in HER2-Expressing Gyn Cancersѻý> More responses, longer OS in subset with the highest levels of HER2 expression Nov 07, 2023
<ѻý>Sexual Health Suffered After Radical Hysterectomy for Early Cervical Cancerѻý> Compared with simple hysterectomy, analysis shows more sexual toxicities, worse quality of life Nov 07, 2023
<ѻý>Lung Cancer Survival High at 20 Years With Screen-Detected Tumorsѻý> After two decades, lung cancer-specific survival remained at 81% in I-ELCAP program Nov 07, 2023
<ѻý>Mixed Results for Tiragolumab/Atezolizumab Combo in PD-L1+ Recurrent Cervical Cancerѻý> Overall response beats historical benchmark, but misses significance target Nov 06, 2023
<ѻý>RAF/MEK and FAK Inhibitor Combo Effective in Low-Grade Serous Ovarian Cancerѻý> Impressive overall response rate with avutometinib-defactinib in RAMP 201 trial Nov 05, 2023
<ѻý>Maintenance Selinexor May Boost PFS in TP53 Wild-Type Advanced Endometrial Cancerѻý> Particularly strong PFS signal seen in patients that were mismatch repair proficient Nov 05, 2023
<ѻý>Adding Atezolizumab Improves Survival in Advanced Cervical Cancerѻý> Trial confirms the role of first-line checkpoint inhibition in metastatic or recurrent disease Nov 03, 2023
<ѻý>Evidence of Safety, Efficacy for Salvaged Blood Irradiators Lacking, FDA Staff Sayѻý> Devices are aimed at preventing metastasis during surgery Nov 03, 2023
<ѻý>Wearables as Cancer Monitors; No China Price Break; Cancer Mystery in Appalachiaѻý> News, features, and commentary about cancer-related issues Nov 03, 2023
<ѻý>Transitioning Cancer Survivors Away From Oncologic Careѻý> It's time for a new model of care Nov 03, 2023
<ѻý>False-Positive Mammograms May Indicate Higher Breast Cancer Risk in the Futureѻý> Swedish cohort study shows a 61% increased risk over 20 years Nov 02, 2023
<ѻý>Years of Progressing Facial Numbness and Deteriorating Vision Drives Diagnosisѻý> Suspect perineural recurrence of cutaneous squamous cell carcinoma, experts urge Nov 02, 2023
<ѻý>Lambert-Eaton Myasthenic Syndrome Underdiagnosed Alongside SCLC in the U.S.ѻý> Findings suggest patients with SCLC are not screened for LEMS, despite their association Nov 02, 2023
<ѻý>ACS: Millions More Should Get Lung Cancer Screeningѻý> Notably, new recommendations say it doesn't matter when a person quit smoking Nov 01, 2023
<ѻý>Reduced-Dose Schedule of Cabazitaxel Viable for Seniors With mCRPCѻý> Grade 3 or higher neutropenia, neutropenic complications reduced by 12-fold Nov 01, 2023
<ѻý>Potential Cure for Sickle Cell Clears Hurdle for Approvalѻý> FDA advisors suggest the benefits of gene therapy outweigh risks of off-target editing Oct 31, 2023
<ѻý>Personalized Intervention Helps CRC Screening Decisions for Older Adultsѻý> Patients receiving intervention were less likely to undergo screening if benefits were low Oct 31, 2023