乌鸦传媒

Oncology/Hematology

<乌鸦传媒 class='mpt-top_cat_title_description'>News, opinions and meeting coverage in oncology/hematology.

<乌鸦传媒>Bodybuilders Bulk Up Using ... Cancer Drugs?

While steroids are all-stars among performance-enhancing drugs, breast cancer drugs are a lesser-known staple of doping regimens, as are some investigational agents that aren't available on any regulated market.

<乌鸦传媒>Combo Active in Neuroendocrine Cancers

SAN FRANCISCO -- More than 90% of patients with neuroendocrine tumors had objective responses or stable disease when treated with an off-the-shelf chemotherapy doublet, results of a small study showed.

<乌鸦传媒>Colonoscopies: The Longer the Better

Polyp and adenoma detection rates were highest when the colonoscopy withdrawal time was 9 minutes long, near the upper limit of the recommended 6 to 10 minutes withdrawal time, researchers found.

<乌鸦传媒>Jakafi Requires Careful Dosing Early: Experts

NEW YORK -- The JAK inhibitor can make a big difference for myelofibrosis patients, but must be monitored.

<乌鸦传媒>OncoBlog: Driving the CAR to a Cancer Cure?

Is immunotherapy with chimeric antigen receptor (CAR)-directed T cells the "next big thing" in oncology? Presentations and discussion at a recent conference suggest the technology has considerable promise -- but will it qualify as a breakthrough? OncoBlog is a blog by the Medpage Today staff for readers with an interest in oncology. This post comes from Charles Bankhead.

<乌鸦传媒>Arimidex: Top Drug for Breast Ca Prevention?

SAN ANTONIO -- Should anastrozole (Arimidex) be the first choice in pharmacologic primary prevention of breast cancer, based on IBIS-II trial results presented here? No, said most experts.

<乌鸦传媒>FDA: Nipple Test No Substitute for Mammogram

A nipple aspirate test shouldn't take the place of mammography or otherwise be used on its own to screen for breast disease, the FDA warned.

<乌鸦传媒>Gene Therapy Works in SCID With No Risk of Leukemia

NEW ORLEANS -- Genetic therapy appeared to restore the immune system of patients with X-linked severe combined immunodeficiency (SCID), but without leading to leukemia as a side effect, researchers reported here.

<乌鸦传媒>Radiation Safe in Unbiopsied Lung Cancer

CHICAGO -- Treating people with stereotactic body radiation for suspected -- but unbiopsied -- lung cancers appears to allow for acceptable local control of the disease with low toxicity, researchers reported here.

<乌鸦传媒>High IgG Signals Autoimmunity in Kids

High levels of immunoglobulin G (IgG) in children -- and particularly girls -- were associated with the development of autoimmune disease, researchers found.

<乌鸦传媒>ACA: When Is a Screening Not a Screening?

A provision in the Affordable Care Act that waives patients' payments for colonoscopies is an example of how good intentions in the law can lead to a tangle of unforeseen consequences.

<乌鸦传媒>Prime Time: Skin Docs Name 5 Unnecessary Procedures

The American Academy of Dermatology joined more than 80 other medical societies in the Choosing Wisely campaign, naming five treatments or procedures that may not be necessary. Prime Time is a blog by Chris Kaiser for those interested in primary care.

<乌鸦传媒>Stem Cells Help ALD Kids Live Longer

AUSTIN, Texas -- Survival in children with cerebral adrenocerebral adrenoleukodystrophy (ALD) appeared to be improved with allogeneic hematopoietic cell transplants compared with untreated patients, a researcher said here.

<乌鸦传媒>Few Lupus, IBD Patients Getting HPV Vaccine

SAN DIEGO -- Despite being at greater risk of infection, few children and young adults with autoimmune diseases are being vaccinated against human papillomavirus, according to a study.

<乌鸦传媒>TSH Suppression: More Harm Than Good After Cancer Surgery?

SAN JUAN -- Suppressing thyroid-stimulating hormone (TSH) after thyroidectomy for low-risk cancer increases the risk of osteoporosis in women without cutting back on cancer recurrence, researchers reported here.

<乌鸦传媒>Morning Break: Addictive Oreos and Sperm-Slaying Bacon

Health news and commentary from around the Web, gathered by the 乌鸦传媒 staff.

<乌鸦传媒>'Nose Knows' Devices Not Ready for Clinic

BARCELONA -- Within a decade, doctors may be able to diagnose cancer, asthma, and tuberculosis simply by having an electronic nose analyze a person's breath, researchers reported here.

<乌鸦传媒>Lab Notes: Meth May Worsen Fungal Infection

Mice injected with methamphetamine and exposed to Cryptococcus fungi showed more extensive and hard-to-eradicate infections. Also this week: an organic pesticide fights parasitic worms.

<乌鸦传媒>Losing a Tattoo, Gaining a Tumor

An unintended consequence of laser tattoo removal in a 29-year-old man was a diagnosis of malignant melanoma, according to a German case report.

<乌鸦传媒>Oncology Clinics Caught in Financial Vise

Community oncology clinics continue to feel the squeeze of a changing reimbursement structure that has forced 288 clinics to close in the past 6 years.

<乌鸦传媒>Medicare to Pay for More FDG-PET Scans

WASHINGTON -- Up to three scans using 18F-fluorodeoxyglucose-enhanced positron emission tomography technology can be covered by Medicare for oncology treatment planning, the Centers for Medicare and Medicaid Services said.

<乌鸦传媒>ASCO: Vinegar Test May Reduce Cervical Ca Deaths

CHICAGO -- Vinegar has been used for everything from cleaning refrigerators to taming foot odors, and now this common kitchen staple may reduce cervical cancer deaths as well, researchers reported here.

<乌鸦传媒>ASCO: Two Taxol Regimens Similar in Breast Cancer

CHICAGO -- Breast cancer patients obtained the same disease control with less toxicity when they received weekly low-dose chemotherapy instead of a higher dose given every 2 weeks, results of a randomized trial showed.

<乌鸦传媒>ASCO: Targeted Agent Has Slim NSCLC Benefit

CHICAGO -- The novel kinase inhibitor nintedanib may slightly delay relapse of non-small cell lung cancer when added to chemotherapy, with perhaps greater benefit in adenocarcinomas, the LUME-Lung 1 trial showed.

<乌鸦传媒>ASCO: Herpes-Derived Tx for Melanoma?

CHICAGO -- Intralesional injection of an oncolytic therapy significantly increased the durable response rate in advanced melanoma compared with a control therapy, according to results of a randomized trial.

<乌鸦传媒>ASCO: Immune Therapy Durable in Melanoma

CHICAGO -- A therapy aimed at reviving the immune response to advanced melanoma generated durable responses in long-term follow-up of an early clinical trial, a researcher said here.

<乌鸦传媒>ASCO: Targeted Rx Slows Ovarian Ca Progression

CHICAGO -- Adding the oral anti-angiogenesis drug pazopanib (Votrient) to chemotherapy extended disease-free survival by an average of 5.6 months, a phase III study showed.

<乌鸦传媒>Sjogren's Carries Heavy Disease Burden

BIRMINGHAM, England -- Patients with primary Sjogren's syndrome are prone to develop serious complications over the long term, despite the presumption that this is a relatively benign autoimmune disease, a 25-year review found.

<乌鸦传媒>Fatal Reactions Prompt Omontys Recall

All lots of the new anemia drug peginesatide (Omontys) have been recalled because of severe hypersensitivity reactions -- some fatal -- observed after the drug was approved last March.

<乌鸦传媒>Zytiga Prolongs Prostate Cancer Survival

ORLANDO -- Survival improved and disease progression slowed in men with metastatic castration-resistant prostate cancer treated in first line with abiraterone acetate (Zytiga).

<乌鸦传媒>Steroids Reduce Benefits of Prostate Ca Tx

ORLANDO -- Men with castration-resistant prostate cancer had worse survival when treated with corticosteroids, regardless of their primary treatment, a post-hoc analysis of a randomized trial showed.

<乌鸦传媒>Early Radiation Boosts Prostate Cancer Survival

ORLANDO -- Immediate radiation therapy after radical prostatectomy led to a 50% increase in long-term biochemical progression-free survival for patients with locally advanced prostate cancer, according to a study reported here.

<乌鸦传媒>Surgery Boosts Outcomes in Esophageal Cancer

SAN FRANCISCO -- Surgery after chemoradiotherapy increased overall and disease-free survival compared with chemoradiotherapy alone in advanced esophageal cancer treatment, researchers reported here.

<乌鸦传媒>Judge OKs $762 Million Deal in Aranesp Case

A federal judge approved a $762 million settlement Wednesday in a case involving Amgen's off-label promotion of darbepoetin alfa (Aranesp), an anemia drug.

<乌鸦传媒>Amgen Agrees to Pay $762 Million in Aranesp Case

The biotech drug giant Amgen pled guilty Monday to promoting its blockbuster anemia drug darbepoetin alfa (Aranesp) for off-label dosing regimens, agreeing to pay $762 million in fines.

<乌鸦传媒>Infection High in Myeloma, with High Mortality

ATLANTA -- More than a fifth of patients with multiple myeloma died of infection within a year of diagnosis, Swedish investigators reported here.

<乌鸦传媒>Oral Azacitidine Safe, Effective in Low-Risk MDS

ATLANTA -- Oral azacitidine (Vidaza) given for up to 21 days per 4-week cycle for myelodysplastic syndrome appeared safe and effective in patients with lower-risk disease, a researcher said here.

<乌鸦传媒>Metformin Role in Breast Cancer Still Unclear

SAN ANTONIO -- Clinical trials of the diabetes drug metformin in breast cancer yielded a few possible clues to anticancer activity but little else, according to a series of reports.

<乌鸦传媒>New Combo Replaces CHOP for Lymphoma

ATLANTA - The combination chemotherapy known as CHOP, used for nonHodgkin's lymphoma, is rapidly being replaced by bendamustine (Treanda), frequently combined with rituximab (Rituxan), researchers reported.

<乌鸦传媒>Effexor May Not Mix with Tamoxifen

SAN ANTONIO -- The antidepressant venlafaxine (Effexor), often given to breast cancer patients to treat the hot flashes associated with tamoxifen therapy, might reduce the effectiveness of the drug, a researcher said here.

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