<ѻý>Targeting New Pathways to Improve Outcomes in Renal Cell Carcinomaѻý> Building on recent success requires intervention at multiple steps in the cancer immunity cycle Nov 14, 2023
<ѻý>No Boost in Outcomes for Clear Cell RCC With Higher Belzutifan Doseѻý> A quarter of patients responded whether at the recommended or higher dose Nov 13, 2023
<ѻý>Tyrosine Kinase Inhibitor Active in Heavily Treated Renal Cell Carcinomaѻý> Responses to "special drug" zanzalintinib in cabozantinib-exposed and unexposed patients Nov 11, 2023
<ѻý>Randomized Trial Backs HIF-2a Inhibition in Advanced RCCѻý> After immunotherapy-TKI failure, belzutifan produces better outcomes versus everolimus Oct 24, 2023
<ѻý>SABR Offers New Hope for Older Patients With Inoperable Kidney Cancerѻý> Phase II study shows 100% local control and cancer-specific survival after more than 3 years Oct 01, 2023
<ѻý>Adjuvant Everolimus Falls Short in High-Risk Renal Cancerѻý> However, the drug did show benefit in a subgroup at highest risk of recurrence after nephrectomy Jul 31, 2023
<ѻý>Upfront Systemic Therapy, Deferred Surgery Pass Muster in Advanced Kidney Cancerѻý> Two studies suggest no harm from deferred cytoreduction, potential benefits of immunotherapy May 02, 2023
<ѻý>CAR T-Cell Therapy Shows Promise in Advanced Kidney Cancerѻý> ORR of 30% in patients with CD70-positive disease using off-the-shelf, allogeneic product Apr 19, 2023
<ѻý>Post-Immunotherapy Combo Promising in Advanced RCCѻý> Duration of response reaches 18.6 months with belzutifan plus cabozantinib Apr 03, 2023
<ѻý>Novel PET Imaging Agent Accurately IDs Clear Cell Renal Cancersѻý> ZIRCON trial meets sensitivity and specificity targets Mar 13, 2023
<ѻý>Combo Falters in Papillary Renal Cancer, but Some Promise in MET-Driven Subsetѻý> Over 50% of patients with advanced MET-driven tumors responded to savolitinib plus durvalumab Feb 24, 2023
<ѻý>ICI/TKI Combo Maintains Survival Benefit in Advanced RCCѻý> Updated trial data show nivolumab/cabozantinib doublet "is getting better with age" Feb 20, 2023
<ѻý>Pre-Op Axitinib Helps for Partial Nephrectomy of Complex Renal Tumorsѻý> Approach in small ongoing trial resulted in reduction in tumor size and complexity Dec 02, 2022
<ѻý>Allogeneic CAR T-Cell Therapy Shows Early Promise in Kidney Cancerѻý> CTX130 yields sustained complete response in one patient with relapsed/refractory disease Nov 15, 2022
<ѻý>Role of Cytoreductive Nephrectomy Unclear for Dedifferentiated Kidney Cancerѻý> Thirteen-month survival gain falls short of statistical significance in observational study Nov 10, 2022
<ѻý>Immune Stimulator May Enhance Targeted Therapy's Activity in Metastatic RCCѻý> Numerical advantage in median survival, response rate, durability with dendritic-cell agent Nov 09, 2022
<ѻý>Immunotherapy Doublet Shows Promise for Nonsurgical Control of Small Kidney Cancersѻý> Nivolumab/ipilimumab achieves 1-year PFS of 100% in unresectable T1N0M0 tumors Nov 07, 2022
<ѻý>Probiotic May Rev Up Response to Immunotherapy in Advanced Kidney Cancerѻý> Dramatic slowing of disease progression, prolonged responses with microbiome modulator Nov 06, 2022
<ѻý>Triplet in First-Line Kidney Cancer Thwarts Disease Progressionѻý> Randomized study shows "clinically meaningful" PFS improvement over dual immunotherapy alone Sep 13, 2022
<ѻý>Three Adjuvant Immunotherapy Trials Flop in Renal Cell Carcinomaѻý> Studies appear to contradict benefit previously shown with pembrolizumab in this setting Sep 12, 2022
<ѻý>Fewer Complications With Robotic Nephrectomy in Complex Kidney Tumorsѻý> However, trial comparing robotic and open surgery was stopped early due to low enrollment Jul 06, 2022
<ѻý>Oral Retinoid May Ease Painful Skin Reactions to Anticancer Therapyѻý> Preliminary data on acitretin therapy are promising May 11, 2022
<ѻý>Check Troponin in RCC Patients Before Checkpoint-VEGFR Inhibitor Comboѻý> In JAVELIN Renal 101, those with high levels had more heart events with avelumab-axitinib Mar 05, 2022
<ѻý>FDA OKs PD-1 Inhibitor for Adjuvant Treatment of Kidney Cancerѻý> Key trial showed 32% reduction in risk of recurrence with pembrolizumab Nov 18, 2021
<ѻý>Cabozantinib Shows Activity Against RCC Brain Metastasesѻý> Retrospective study reported intracranial responses in about one half of patients Oct 22, 2021
<ѻý>'A Quantum Leap Forward': Potential New Standard in High-Risk RCCѻý> Adjuvant immunotherapy led to 32% reduction in the risk of recurrence, positive trend in OS Jun 03, 2021
<ѻý>How Did a Patient Survive a Decade With Metastatic RCC?ѻý> Surgery had beneficial role May 17, 2021
<ѻý>A CLEAR Upfront Winner in Advanced RCC?ѻý> Pembrolizumab-lenvatinib makes splash with longest PFS benefit in RCC recorded to date Feb 14, 2021
<ѻý>Practice-Changing Trial in Metastatic Papillary RCCѻý> Cabozantinib improved PFS, response rates over sunitinib Feb 14, 2021
<ѻý>Another First-Line Combo Succeeds in Advanced RCCѻý> Third immunotherapy plus TKI combination tops sunitinib Sep 19, 2020
<ѻý>Olympic Ice Dancer's Renal Cell Carcinomaѻý> Maia Shibutani is "embracing the moment" and raising money for healthcare workers Sep 10, 2020
<ѻý>Cancer Immunotherapy Tied to Severe COVID-19 Outcomesѻý> Nearly threefold increased risk of hospitalization, severe respiratory illness Jun 25, 2020
<ѻý>6-Week Keytruda Safe, Effective in Melanomaѻý> Schedule gets FDA approval for all adult indications Apr 30, 2020
<ѻý>DOAC Works in Cancer-Related VTE, No Tradeoff in Bleedsѻý> Apixaban monotherapy matches dalteparin in non-inferiority trial Mar 29, 2020
<ѻý>Are Low-Density Incidental Renal Masses Being Misdiagnosed?ѻý> New study raises concerns about criteria for benign cysts vs aggressive renal cancer Dec 23, 2019
<ѻý>Metastatic Renal Cell Carcinoma: Watch for Brain Metsѻý> Present in roughly 5% of patients, survival worse in patients with larger or more lesions Nov 18, 2019
<ѻý>Long-Term Surveillance Safe for Small Renal Tumorsѻý> Two cases of metastasis, one cancer death after almost 5 years of follow-up Jun 13, 2019
<ѻý>Surgery Delay OK for Most With Renal Cell Carcinomaѻý> Two studies add support for active surveillance for small tumors May 08, 2019
<ѻý>Do Keloids Convey a Higher Cancer Risk?ѻý> Taiwanese researchers show association between raised scars and cancers Mar 03, 2019
<ѻý>No Survival Bump Yet with Tivozanib for RCCѻý> Selected studies on kidney cancer from the Genitourinary Cancers Symposium Feb 18, 2019