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News, opinions and meeting coverage in hospital-based medicine.

A photo of physicians tending to a severe COVID patient in the ICU.

<乌鸦传媒>Don't Try ARBs for Severe COVID, Trial Indicates

Harms seen without any compensating survival benefit

A computer rendering of bacteria in the blood.

<乌鸦传媒>Extended-Infusion Antibiotics Tied to Reduced Mortality From Bloodstream Infections

Benefit limited to patients with severe illness or elevated minimum inhibitory concentrations

A photo of a nurse interacting with a hospitalized COVID patient while two other nurses tend to them.

<乌鸦传媒>Delirium During COVID Hospitalization Raises Disability, Cognitive Risks

At-risk older adults should be screened, referred early for rehabilitation, researcher urges

ADA over a photo of Orange County Convention Center in Orlando, FL

<乌鸦传媒>In-Hospital Continuous Glucose Monitoring Can't Budge T2D Control

Randomized trial failed to get anywhere near tight glucose control

A photo of a vital signs monitor and a nurse tending to a patient in the ICU.

<乌鸦传媒>SGLT2 Inhibitor No Help for ICU Patients With Acute Organ Dysfunction

Secondary findings of trial only suggest a potential benefit in kidney protection

A computer rendering of a stomach ulcer.

<乌鸦传媒>PPI Prevents Upper GI Bleeds During Intubation, With No Effect on Mortality

But expert still suggests the approach may not be appropriate for the most severely ill

ATS over a photo of the San Diego Convention Center

<乌鸦传媒>Acetaminophen Fails to Improve Mortality, Need for Organ Support in Sepsis

However, treated patients were less likely to develop ARDS, respiratory dysfunction

PAS over a photo of Metro Toronto Convention Center in Toronto, Canada

<乌鸦传媒>More Newborns Intubated on First Try With Video Laryngoscopy

"Unusually high degree" of successful first attempts in trial, researchers say

A nurse feeding a premature baby with a syringe.

<乌鸦传媒>No Best Nutrition Strategy for Most Preemies Waiting to Breastfeed

Trial in moderate to late preterm infants comparing a variety of common methods finds no winner

FDA APPROVED Sepsis ImmunoScore over a photo of the application on an iPad.

<乌鸦传媒>AI Sepsis Diagnostic Tool Gets FDA Authorization

EHR-embedded software algorithm uses biomarkers, clinical data

A photo of a male nurse steadying a walker his patient is holding onto.

<乌鸦传媒>Mobilizing ICU Patients May Not Affect Risk of Adverse Events, Death

Implementing mobilization tied to a less than 3% risk of adverse events in meta-analysis

A photo of a high-flow nasal cannula

<乌鸦传媒>Weight-Based High-Flow Oxygen for Bronchiolitis May Reduce ICU Admissions

A weight-based high-flow nasal cannula protocol tied to 6.1% decrease per year in ICU admission

A photo of a nurse holding the tubing of a ventilated patient in the intensive care unit.

<乌鸦传媒>Algorithm May Help Determine Oxygen Targets for Mechanically Ventilated Adults

If results are "true and generalizable, then the consequences are staggering," editorialist says

A scanning electron micrograph of methicillin-resistant Staphylococcus aureus surrounded by cellular debris

<乌鸦传媒>Staph Infections Appear to Be More Deadly for Women

Understanding reasons behind mortality gap is "of critical importance," study author says

An x-ray image of a patient's lungs with aspiration pneumonia

<乌鸦传媒>Study Backs Recommended Antibiotic Approach for Aspiration Pneumonia

Evidence of more side effects, lack of survival benefit with extended anaerobic coverage

A photo of a woman with a an intravenous line in her arm.

<乌鸦传媒>Midline Catheters Go Head-to-Head With PICCs for Bloodstream Infections

For dwell times of 15 days or less, midline catheters noninferior, single-center study finds

FDA ADCOMM Pulse oximeters over a photo of one on a man鈥檚 finger.

<乌鸦传媒>FDA Advisory Panel Generally Pleased With Pulse Oximetry Clinical Trial Proposal

But some questions arose regarding number of participants, permissible variance in measurements

A photo of a premature infant in an incubator.

<乌鸦传媒>Donor Milk, Formula Go Head-to-Head for Extreme Preemies in the NICU

Similar neurodevelopmental outcomes, but less necrotizing enterocolitis with donor milk

SCCM over a photo of Phoenix Convention Center

<乌鸦传媒>Critical Care Guideline Changes Boost Corticosteroid Uses, Role of Families

Corticosteroids, glycemic control, and clinical deterioration outside ICU addressed

A photo of a woman holding a premature infant

<乌鸦传媒>Ibuprofen Fails Another Crack at Reducing Preemie Lung Issues and Deaths

A therapy to help babies with hole in heart is still lacking

SCCM over a photo of Phoenix Convention Center

<乌鸦传媒>Can Targeting Normoxemia Benefit Critically Ill Trauma Patients?

Strategy appeared to increase supplemental oxygen-free days

SCCM over a photo of Phoenix Convention Center

<乌鸦传媒>Tailoring Drug Interaction Alerts to the ICU Reduced Number of High-Risk Combos

Intervention reduced "alert fatigue" for clinicians

SCCM over a photo of Phoenix Convention Center

<乌鸦传媒>Ceftriaxone Prevents Ventilator-Associated Pneumonia After Brain Injury

Single-dose administered prophylactically associated with less pneumonia, mortality

A photo of an intubated woman in the intensive care unit

<乌鸦传媒>Diagnostic Errors Common in Hospital Deaths, ICU Transfers, Study Suggests

Mistakes were driven by patient assessment, testing, and often led to harm or death

A photo of nurses in protective gear tending to a patient in the covid ICU.

<乌鸦传媒>Inpatient COVID-19 Costs Substantially Outpaced Medical Inflation

Hospital costs to treat COVID-19 estimated at a staggering $70 billion

A photo of an infant receiving mechanical ventilation in the intensive care unit.

<乌鸦传媒>Giving Oropharyngeal Surfactant at Birth Is No Help to Preemies

Increased rates of pneumothorax emerged among newborns treated prophylactically

A photo of a little boy receiving mechanical ventilation in the intensive care unit.

<乌鸦传媒>Conservative Oxygenation Outperforms Liberal Targets for Critically Ill Kids

Oxy-PICU is the first randomized trial to compare different SpO2 targets in these patients

A photo of intensive care unit nurses turning over a covid patient.

<乌鸦传媒>Prone Positioning Falls Flat for Weaning COVID Patients Off ECMO

Similar ECMO duration, mortality compared with supine position in randomized trial

A photo of a nurse holding intubation equipment in the intensive care unit.

<乌鸦传媒>Safer to Hold Off on Intubating Comatose, Intoxicated Patients, Trial Finds

French centers showed faster discharge, fewer adverse events

A photo of a nurse in full protective gear checking on her patient in the COVID intensive care unit.

<乌鸦传媒>Vitamin C Flops for Severe COVID-19

Trial data suggest chance of harm significantly greater than small possibility of efficacy

A computer rendering of a ruptured artery.

<乌鸦传媒>Cryoprecipitate, REBOA Flop for Improving Major Hemorrhage Outcomes

The first randomized trials of both approaches failed

CHEST over a photo of the Hilton Hawaiian Village Waikiki Beach Resort in Honolulu, HI.

<乌鸦传媒>ECMO Has Become a Harder Sell in Severe COVID-19

Studies show decreased use, cast doubt on clinical benefit

CHEST over a photo of the Hilton Hawaiian Village Waikiki Beach Resort in Honolulu, HI.

<乌鸦传媒>'Surprising' Contribution of Pulmonary Hypertension to ARDS Outcomes

Coexisting conditions spell markedly poor clinical course

A photo of a female nurse holding a bag of blood for transfusion.

<乌鸦传媒>Overdoing Blood Transfusions? JAMA Special Issue Shines a Light

Also includes two negative trials in hemorrhage control

A close up of the tubing of a hospitalized patient on mechanical ventilation

<乌鸦传媒>Low Tidal Volume Compliance Still Lacking in Mechanical Ventilation

Women, shorter patients, those with a high BMI more likely to receive higher tidal volumes

A close up photo of a bag of parenteral nutrition

<乌鸦传媒>No Benefit to Tight Glucose Control in ICU

Trial attempts to settle the controversy once and for all

A photo of Madonna in the press room at the 2018 MTV Video Music Awards

<乌鸦传媒>Madonna's ICU Stay May Have Been Due to Sepsis

Despite being life-threatening, sepsis can be easy to miss

A photo of an intubated male patient in the intensive care unit.

<乌鸦传媒>Sepsis Outcomes No Different With Prolonged Beta-Lactam Antibiotic

Death and drug resistance unchanged no matter the duration of treatment

A photo of a CPAP mask.

<乌鸦传媒>Breathing Support Type Matters for Preventing Extubation Failure in the PICU

CPAP, BiPAP, nasal cannula compared with conventional oxygen therapy

A photo of a female nurse in full protective gear standing at the bedside of a senior man wearing a helmet CPAP.

<乌鸦传媒>Helmet CPAP Leads Noninvasive Ventilation Therapies for Acute Respiratory Failure

Showdown of HFNC and helmet- and face mask-based modalities in meta-analysis

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