<ѻý>Adjuvant Anti-PD-1 Misses on OS in High-Risk Melanomaѻý> But pembrolizumab topped active controls for relapse-free survival Jun 07, 2021
<ѻý>Combination Shows Promise in Post-Osimertinib Lung Cancerѻý> Responses in 36% with amivantamab-lazertinib, 47% with EGFR/MET resistance Jun 06, 2021
<ѻý>Novel CDK 4/6 Inhibitor Proves Mettle in HR+/HER2- Advanced Breast Cancerѻý> Dalpiciclib may be a new treatment option; palbociclib and ribociclib continue to shine Jun 06, 2021
<ѻý>Perioperative Chemo Enough in Esophageal Cancer?ѻý> MAGIC/FLOT regimens yielded similar overall survival to multimodal CROSS regimen Jun 06, 2021
<ѻý>CAR-T Drives High Response in Relapsed/Refractory ALLѻý> ZUMA-3 study shows brexucabtagene autoleucel offers long-term clinical benefit Jun 06, 2021
<ѻý>Antibody-Drug Conjugate Active in Resistant Lung Cancerѻý> Responses in 39% of EGFR inhibitor-resistant patients with patritumab deruxtecan Jun 05, 2021
<ѻý>Chemoimmunotherapy Tied to Better Outcomes in Advanced NSCLCѻý> PD-L1 status and age play key roles in success of combined regimen versus immunotherapy alone Jun 05, 2021
<ѻý>Combination Therapy Achieves High Response in Ph+ ALLѻý> Ponatinib-blinatumomab offers promising regimen in frontline and relapse/refractory disease Jun 05, 2021
<ѻý>Small PFS Bump in Synovial Sarcoma With Novel Drugѻý> But questions raised over control arm and whether improvement represents a meaningful benefit Jun 05, 2021
<ѻý>Radioligand Therapy Boosts Survival in Metastatic CRPCѻý> PSMA-directed agent improved overall survival by median 4 months Jun 04, 2021
<ѻý>Adding Chemo to Standard Care No Help for Cervical Cancerѻý> Similar OS, PFS, and patterns of recurrence, with more toxicity Jun 04, 2021
<ѻý>PD-1 Inhibitor Shows Benefit in Nasopharyngeal Cancerѻý> Toripalimab plus first-line chemo improved survival in recurrent/metastatic disease Jun 03, 2021
<ѻý>Olaparib Wins in Early BRCA-Mutant Breast Cancerѻý> First trial to show adjuvant PARP inhibitor benefit inBRCA mutation carriers Jun 03, 2021
<ѻý>Survival Boost With First-Line Immunotherapy for Esophageal Cancerѻý> Nivolumab plus ipilimumab or chemo offers new option for advanced, metastatic disease Jun 03, 2021
<ѻý>'A Quantum Leap Forward': Potential New Standard in High-Risk RCCѻý> Adjuvant immunotherapy led to 32% reduction in the risk of recurrence, positive trend in OS Jun 03, 2021
<ѻý>Vaccination, Screening Succeeds in Cervical and Prostate Cancersѻý> Cervical cancer rates on the decline; PSA testing benefits younger Black men May 19, 2021
<ѻý>PD-L1 Inhibitor Thwarts Recurrence in Early Lung Cancerѻý> Risk of death, recurrence 34% lower with atezolizumab after surgery and chemo May 19, 2021
<ѻý>Novel Immunotherapy Boosts Melanoma Outcomesѻý> Adding LAG-3 checkpoint inhibitor to nivolumab extended PFS in patients with advanced disease May 19, 2021
<ѻý>High Marks for CAR T Cells in R/R Myelomaѻý> Response rates of 70-100% with BCMA-targeted products for heavily treated disease Jun 03, 2020
<ѻý>Second Surgery Gets OS Win in Recurrent Ovarian Cancerѻý> Survival improved by nearly 8 months with cytoreductive surgery at first relapse Jun 02, 2020
<ѻý>Early Palliation: Boon for AML Patients on Intensive Chemoѻý> Intervention led to marked improvements in QoL, mental distress, end-of-life care Jun 02, 2020
<ѻý>Pembrolizumab May Help in Triple-Negative Breast Cancerѻý> Upfront therapy extends progression-free survival in metastatic disease, study shows Jun 01, 2020
<ѻý>Surgery for Metastatic Breast Cancer Fails to Boost Overall Survivalѻý> Cumulative data, though, don't rule out benefit for selected patients with de novo stage IV disease Jun 01, 2020
<ѻý>Add-On Tucatinib Ups Survival in Breast Cancer With Brain Metsѻý> TKI plus trastuzumab-capecitabine reduced risk of death by nearly half Jun 01, 2020
<ѻý>VRd Still Reigns in Newly Diagnosed Myelomaѻý> KRd fails to prove superiority in head-to-head trial Jun 01, 2020
<ѻý>CAR T-Cell Therapy Impresses in Indolent NHLѻý> Overall response rate exceeding 90% with axi-cel in relapsed/refractory setting May 31, 2020
<ѻý>Oral ADT Slashes Heart Risk in Advanced Prostate Cancerѻý> Novel GnRH antagonist has potential to be new standard, says researcher May 30, 2020
<ѻý>Sentinel Node Biopsy Proves Mettle in H&N Cancerѻý> Senti-MER study results establish SN biopsy as standard of care, researcher says May 30, 2020
<ѻý>Studies Make Case for Hormonal Therapy in nmCRPCѻý> Prolonged survival with three different androgen signaling inhibitors May 30, 2020
<ѻý>HCQ Linked to Harm in Cancer Patientsѻý> Combination with azithromycin associated with three-fold risk of mortality, registry study shows May 28, 2020
<ѻý>New First-Line Standard in Metastatic Bladder Cancerѻý> "High bar to beat" as avelumab maintenance improves median survival by over 7 months May 28, 2020
<ѻý>Paradigm Shift Coming for Early NSCLC?ѻý> Postoperative osimertinib doubles DFS in patients with stages Ib-IIIa EGFR+ lung cancer May 28, 2020
<ѻý>CAR T Cells Show Activity in Solid Tumorsѻý> High response rate in mesothelioma, shrinkage of gastric, pancreatic tumors Jun 07, 2019
<ѻý>Keytruda 'Switch' Extends PFS in Advanced Bladder Cancerѻý> Matthew Galsky, MD, discusses possible role of maintenance PD-1 blockade Jun 06, 2019
<ѻý>Jury Out on Margetuximab in Advanced HER2+ Breast Cancerѻý> One-month PFS boost, but certain subgroups may derive more benefit Jun 05, 2019
<ѻý>Depth of Tumor Response a Better Survival Predictorѻý> Could improve on RECIST as outcome measure in oncology Jun 05, 2019
<ѻý>Preop Chemo Reduces CRC Surgical Morbidityѻý> Lower 2-year recurrence rate versus adjuvant therapy but not significantly Jun 04, 2019
<ѻý>Good News Continues for Enfortumab Vedotin in Bladder Caѻý> Phase II trial offers longer survival in difficult disease Jun 04, 2019
<ѻý>'Unprecedented' Survival Benefit Vanishes in Confirmatory Cancer Trialѻý> Over $500 million in sales for drug with possibly no benefit Jun 03, 2019