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Sleep-Dementia Link; Neanderthal Mini-Brains; MS Tx and COVID Vax

<ѻý class="mpt-content-deck">— News and commentary from the world of neurology and neuroscience
MedpageToday
Brain scan images with NeuroBreak in the center.

Sleeping fewer than 5 hours a night was linked to in older adults. (Aging)

Posture, gait, and quality of life tended to improve at 6 months and 1 year in people with bilateral implanted that electrically stimulated vestibular nerve branches. (New England Journal of Medicine)

AC Immune boasted of "remarkable" interim findings from its phase Ib/IIa trial of a , but it's not clear just what those findings are. (Endpoints News)

Researchers generated tiny, lab-grown brain organoids -- also known as "mini-brains" -- containing a , Neanderthals and Denisovans. (Science)

SPECT imaging with 123I-FP-CIT, a radioactive compound that binds to dopamine transporters, from Alzheimer's and Parkinson's in a small study. (Journal of Neurology, Neurosurgery, and Psychiatry)

There's widespread use of cell-based therapies for Parkinson's disease outside of carefully controlled clinical trials, a Movement Disorder Society position paper said.

Sanofi's venglustat failed a phase II study of mutations. (FierceBiotech)

Men who treated terazosin (Hytrin), doxazosin (Cardura), or alfuzosin (Uroxatral) had lower risk of Parkinson's disease than men who used tamsulosin (Flomax), which doesn't affect glycolysis. (JAMA Neurology)

Rapid tapering of who required high doses along with azathioprine therapy appeared to be well tolerated and associated with good outcomes. (JAMA Neurology)

The National Multiple Sclerosis Society issued guidelines about with COVID-19 vaccinations.

Pooled patient-level data from two failed studies suggested patent foramen ovale frequency. (Journal of the American College of Cardiology)

About 8% of people with , with more than half reporting beneficial clinical effects, a German survey showed. (Journal of Parkinson's Disease)

  • Judy George covers neurology and neuroscience news for ѻý, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more.