<ѻý>Forego Radiotherapy for Women With Low-Risk Luminal A Breast Cancer?ѻý> Study shows 5-year local recurrence rate of 2.3% with lumpectomy and endocrine therapy alone Jun 07, 2022
<ѻý>Trastuzumab Deruxtecan Ushers in New Treatment Era for HER2-Low Breast Cancerѻý> DESTINY-Breast04 extends agent's benefits to historically tough-to-treat disease Jun 05, 2022
<ѻý>Capivasertib-Fulvestrant Combo Ups Survival in ER+/HER2- Metastatic Breast Cancerѻý> But benefit seems to be predominantly in patients with PI3K/AKT/PTEN pathway alterations Jun 05, 2022
<ѻý>Sacituzumab Govitecan Boosts PFS in Late-Line HR+/HER2- Metastatic Breast Cancerѻý> "This may be something that really changes the lives of these women for the better," expert says Jun 05, 2022
<ѻý>Adjuvant Everolimus Fails to Stop Recurrence in Early High-Risk Breast Cancerѻý> More than half of everolimus-treated patients permanently discontinued treatment Jun 02, 2022
<ѻý>Prone Beats Supine Positioning for WBRT in Women With Large Breastsѻý> Prone position led to lower rates of moist desquamation May 27, 2022
<ѻý>Black Patients Often Never Given a Chance to Join Breast Cancer Trialsѻý> But survey finds several actionable findings that could boost enrollment May 26, 2022
<ѻý>Vaginal Estrogen 'Underutilized' in Women With GSM After Breast Cancerѻý> Prescribing rate is half that of women with no breast cancer history May 13, 2022
<ѻý>Screening, Early Detection Remain Keys to Lower Cancer Mortalityѻý> Presidential panel sets course to remove barriers, increase services, and improve uptake May 05, 2022
<ѻý>Young Cancer Survivors Face Higher Risk of Death From Second Malignanciesѻý> Study finds 25% higher risk of secondary cancers versus general public, 84% higher risk of death May 04, 2022
<ѻý>Menstrual Cycles Point to Link Between Sex Hormones and Long QTѻý> Research suggests new tools for risk stratification and therapy May 01, 2022
<ѻý>DCIS Recurrence Often Represents a New Primary Breast Cancerѻý> Almost a fifth of cases unrelated to primary DCIS, raising questions about current treatment Apr 11, 2022
<ѻý>RT Prior to Mastectomy, Reconstruction Shows Promiseѻý> U.K. study demonstrates low complication rates and good aesthetic results Apr 08, 2022
<ѻý>Is Sentinel Node Biopsy Necessary for Older Breast Cancer Patients?ѻý> Study finds positive lymph nodes not an indicator for chemotherapy Apr 07, 2022
<ѻý>New Clue to Risk of Peritoneal Cancer After Prophylactic Salpingo-Oophorectomyѻý> Women with BRCA variant and serous tubal intraepithelial carcinoma had a 34-fold greater risk Apr 05, 2022
<ѻý>3D Mammograms Deliver Fewer False-Positive Findingsѻý> However, half of women will have a false positive with annual screening with DBT Mar 25, 2022
<ѻý>FDA OKs PARP Inhibitor as Adjuvant Therapy in Early Breast Cancerѻý> Olaparib (Lynparza) approved for high-risk patients with germline BRCA mutations Mar 14, 2022
<ѻý>Fluorescence-Guided Lumpectomy Shows Promiseѻý> Imaging system reduced the need for re-excision in one-fifth of patients Mar 11, 2022
<ѻý>Androgen Receptor Agonist Active in Resistant ER+ Breast Cancerѻý> Also: Combination targets uncommon form of advanced HER2-mutant disease Mar 09, 2022
<ѻý>More Options for Precision Medicine in Metastatic Triple-Negative Breast Cancerѻý> Moving beyond chemotherapy to immunotherapy, PARP inhibitors, ADCs, combinations Mar 08, 2022
<ѻý>Chipping Away at the Dogma of Axillary Dissection in Breast Cancerѻý> Ongoing trials could help some women avoid even less-invasive sentinel lymph node biopsy Mar 07, 2022
<ѻý>Clinical Picture Brightens for HER2+ Breast Cancer With Brain Metastasesѻý> New therapies breach blood-brain barrier to improve response, survival Mar 07, 2022
<ѻý>Honing the Indications for Adjuvant CDK4/6 Inhibition in Breast Cancerѻý> Defining high risk, considering role of Ki-67, BRCA mutations Mar 05, 2022
<ѻý>Older Patients With Low-Risk DCIS May Not Benefit From Surgery, Radiationѻý> Low rate of invasive recurrence, benefits of surgery and RT limited to patients under 70 Jan 05, 2022
<ѻý>Trastuzumab ADC Active in HER2-Low, HER2-Undetected Breast Cancerѻý> No clear explanation for responses to HER2-targeted drug in HER2-negative tumors Dec 12, 2021
<ѻý>Neratinib-Based Combo Shows Efficacy in HR+, HER2-Mutant Metastatic Breast Cancerѻý> Objective response rate of 42% in patients previously treated with CDK4/6 inhibitors Dec 12, 2021
<ѻý>Benefits of Ovarian Suppression Persist in Premenopausal Breast Cancerѻý> Aromatase inhibitor-ovarian suppression tops tamoxifen strategies at 12-13 years Dec 09, 2021
<ѻý>Highly Mutated Breast Cancer Responds to Immunotherapyѻý> Nivolumab-ipilimumab combination associated with durable response in small study Dec 09, 2021
<ѻý>Ribociclib's OS Benefit in Breast Cancer Seen Regardless of Metastatic Siteѻý> Second analysis shows OS benefit consistent across some intrinsic subtypes as well Dec 09, 2021
<ѻý>No Benefit With Metformin in Early Breast Cancer, Regardless of ER/PR Statusѻý> However, there could be improved outcomes in HER2-positive patients Dec 08, 2021
<ѻý>Small PFS Boost With HDAC Inhibitor for Advanced HR-Positive Breast Cancerѻý> Chinese study contradicts U.S. trial that showed no benefit with entinostat add-on Dec 08, 2021
<ѻý>Black Women Most at Risk for Post-Surgical Lymphedemaѻý> Black women seemed to have triple the odds of swelling after axillary lymph node dissection Dec 08, 2021
<ѻý>TROP2-Directed ADC Promising in Advanced Triple-Negative Breast Cancerѻý> Datopotamab deruxtecan turns in solid phase I results Dec 08, 2021
<ѻý>Novel Endocrine Drug Slows Previously Treated HR-Positive Breast Cancerѻý> Elacestrant led to significant improvement in all patients, ESR1-mutant subgroup Dec 07, 2021
<ѻý>Artificial Intelligence Tool Gets High Marks in Reading Mammogramsѻý> Breast cancer screening results show AI's mettle in real-world dataset Dec 02, 2021
<ѻý>Low-Quality Mammography Leading to More Deaths in Black Women, Says Expertѻý> In cities like Chicago, Black women face higher breast cancer mortality versus white women Oct 26, 2021
<ѻý>No Survival Benefit for Internal Mammary Node Irradiation in Breast Cancerѻý> Women with medially or centrally located tumors may be candidates, however, says researcher Oct 26, 2021
<ѻý>More Evidence for Safety of Accelerated Radiation in Early Breast Cancerѻý> Studies show low toxicity with few recurrences Oct 25, 2021
<ѻý>Analysis Confirms Benefits of CDK4/6 Inhibition in Early Breast Cancerѻý> Reduced risk of recurrence, distant relapse with adjuvant abemaciclib Oct 20, 2021
<ѻý>'Modest' Link Between Infertility and Postmenopausal Breast Cancerѻý> Study finds increased risk for younger women, those with primary infertility Oct 19, 2021