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Clinical Trials

The Spravato nasal spray applicator

<乌鸦传媒>Spravato Debate Still Rages

Journal airs questions about efficacy data, potential for harm

INVESTIGATIVE ROUNDUP over an image of two people looking at computer screens.

<乌鸦传媒>Meet the 'Lien Doctors'; Hidden Clinical Trial Data; Google Nabs More Medical Records

This past week in healthcare investigations

The bottles and pills of Entresto 24 mg, 49 mg, 97 mg

<乌鸦传媒>Entresto Holds Up in the Real World ... But Not for Everyone

Drug not better than ACE inhibitor, ARB for black patients?

An advertisement of LIVEYON PREMIERMAXCB

<乌鸦传媒>FDA Warns Liveyon Over Cord Blood Stem Cell Products

Company slapped for distributing unapproved products, deviating from quality manufacturing practices

ASCO over a photo of McCormick Place in Chicago.

<乌鸦传媒>Depth of Tumor Response a Better Survival Predictor

Could improve on RECIST as outcome measure in oncology

<乌鸦传媒>Want to Know If Someone Is Manipulating Data?

Milton Packer describes how to distinguish science from magic

<乌鸦传媒>Inhaled Hypertonic Saline Safe, Effective in Infants With CF

Study shows that randomized trials are feasible among those under 4 months

<乌鸦传媒>I'm Drowning

A researcher-patient's plea for broader inclusion in cystic fibrosis trials

<乌鸦传媒>State Boards Turn Blind Eye to FDA-Sanctioned Docs

Dozens got warning letters for serious ethical lapses, but nearly all faced no state discipline

<乌鸦传媒>First Clinical Trial in Medicine Changed World History

Milton Packer revisits a 1747 medical landmark and its tortuous aftermath

<乌鸦传媒>TB Vaccine for T1D Study Stirs Controversy

Long-term data suggest BCG vaccine may alter immune attack

<乌鸦传媒>Key Mediterranean Diet Trial Retracted

But republished results show same advantage after excluding protocol violations

<乌鸦传媒>Clinical Trials Need to be More Inclusive, Experts Say

Children, seniors, and chronic disease patients need more options

<乌鸦传媒>'Unsolved Mysteries' on Display at AACR

Large, diverse program reflects rapid pace of advancement

<乌鸦传媒>Gyn Cancer Research Gets Short Shrift in Funding

Mortality-adjusted analysis shows huge disparity versus other cancers

<乌鸦传媒>AHA: Everybody Now Is a Clinical Investigator, Says Califf

Time to revolutionize clinical data gathering, ex-FDA Commissioner urges

<乌鸦传媒>Device May Ease Fistula Creation

Catheter-based, ultrasound-guided device had good long-term patency

<乌鸦传媒>Rituxan Has Promise in Idiopathic Nephropathy

B-cell targeting with rituximab seems as effective as with cyclosporine

<乌鸦传媒>We Have Ruined Late-Breaking Clinical Trials in Cardiology

In this Revolution and Revelation, Milton Packer explains why a cornerstone of annual meetings has gone from sizzler to snoozer

<乌鸦传媒>Vinay Prasad, MD, on 'Medical Reversal'

'Not every reversal puts money in doctors' pockets'

<乌鸦传媒>Vince DeVita鈥檚 Oncology Opus

Medicine and music share center stage in storied career

<乌鸦传媒>Morning Break: Tainted Trials; $40K/Yr Concierge Practice; Reality TV: Diabetes

Health news and commentary from around the Web gathered by the 乌鸦传媒 staff

<乌鸦传媒>Are Propensity Scores As Good As Randomized Trials?

They may not offer much more than multivariable adjustment

<乌鸦传媒>CardioBrief: Serious Questions Raised About Validity Of International Trials

TOPCAT analysis is the 'smoking gun' for trouble from 'offshoring' trials

<乌鸦传媒>Scott Gottlieb's Sham Ideology Rejects Clinical Trials

The next FDA commissioner doesn't believe in trials with sham controls

<乌鸦传媒>MSK Cancer Alliance: Mainly About Medicine

Bi-directional relationship strengthens regional cancer care

<乌鸦传媒>'Jurassic' Clinical Trial Yields Prostate Cancer Guidance

Negative trial informs new studies of adjuvant therapy

<乌鸦传媒>Lies, Damned Lies, and P Values

F. Perry Wilson, MD, delves into the oft-misunderstood statistic

<乌鸦传媒>TCT: For Heart Devices, Will Lag Moving from Europe to U.S. Wane?

FDA Commissioner and E.U. representative talk change

<乌鸦传媒>Why a Missed Primary Endpoint Isn't the End of the Road

Many 'negative' studies would be better described as uninformative

<乌鸦传媒>Afib: Poor Short-Term Outcomes More Common After Stenting

But where is that expected link between Afib and stroke?

<乌鸦传媒>CardioBrief: Diet Drug Loses Another Cardiovascular Outcomes Trial

More chaos over the weight loss drug Contrave

<乌鸦传媒>CardioBrief: Top HF Expert Decries 'Unbelievable Folly' of Clinical Trials and Guidelines

Milton Packer, MD, calls the system to test and evaluate heart failure drugs dysfunctional

<乌鸦传媒>SEER Data Errors: NCI Looks To Avoid Repeats

Results reassuring as SEER audit nears completion

<乌鸦传媒>FDA Presses Pause on Novel Testosterone Product

Gives FDA chance to "back away from the circus," says sponsor's CEO

<乌鸦传媒>Hybrid Academic-Community Cancer Centers Take Shape

Emerging model takes cutting-edge oncology into the community

<乌鸦传媒>HypeWatch: Cannabis Bone-Healing Study Oversold

Forget the headlines you read. Here's what you should know.

<乌鸦传媒>How ASCO'S First Clinical Trial -- TAPUR -- Came To Be

ASCO's entry will evaluate off-label use of targeted agents

<乌鸦传媒>Neurologists Back FDA on Call for ALS Drug Data

Experts want Genervon to release all of its trial results for an investigational ALS drug that's already gained patient support.

<乌鸦传媒>Slippery Slope: Diet Drugs No Help for Heart

In another edition of the Slippery Slope series examining use of surrogate endpoints in drug approvals, 乌鸦传媒 and the Milwaukee Journal Sentinel find diet drugs are approved without solid evidence of benefits, but with hints of harm.

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