<ѻý>FDA Expands Approval of Osimertinib in Lung Cancerѻý> EGFR inhibitor now indicated for unresectable stage III disease following chemoradiotherapy Sep 25, 2024
<ѻý>Cancer Diagnoses Slow to Recover From Effects of COVID Pandemicѻý> Actual rates for 2021 lagged behind projections Sep 25, 2024
<ѻý>Antibody Drug-Conjugate Shows Promising Activity in Extensive-Stage SCLCѻý> Objective response rate was 55% with 12-mg/kg ifinatamab deruxtecan Sep 11, 2024
<ѻý>Added Plinabulin Boosts OS as Later-Line Treatment for EGFR Wild-Type NSCLCѻý> However, plinabulin plus docetaxel still "not ready for prime time," expert says Sep 10, 2024
<ѻý>MET Inhibitor Increases Osimertinib Activity in EGFR+ Advanced NSCLCѻý> Absolute improvement of almost 30%, doubling of duration of response with savolitinib Sep 10, 2024
<ѻý>Perioperative Nivolumab Boosts EFS Versus Neoadjuvant-Only Nivolumab in NSCLCѻý> Two-trial analysis shows about a 40% decreased risk of disease recurrence or death Sep 09, 2024
<ѻý>Ivonescimab Tops Pembrolizumab in PD-L1-Positive, Advanced NSCLCѻý> Novel agent nearly halved risk of progression as first-line therapy in phase III trial Sep 09, 2024
<ѻý>Novel Drugs Boost Immunotherapy Activity in Resectable Lung Cancerѻý> Add-on ADC, monoclonal antibody consistently increase pCR versus PD-1 inhibitor plus chemotherapy Sep 09, 2024
<ѻý>Trial Questions Role of Dual Immunotherapy in First-Line NSCLCѻý> In Japanese trial, nivolumab-ipilimumab didn't improve OS versus pembrolizumab, had more toxicity Aug 22, 2024
<ѻý>Researchers Challenge USPSTF's Lung Cancer Screening Criteriaѻý> Alternate criteria based on years of smoking has higher sensitivity and specificity, study says Aug 20, 2024
<ѻý>Targeted First-Line Combo Approved for EGFR-Mutated Lung Cancerѻý> Lazertinib plus amivantamab improved PFS by about 7 months versus single-agent osimertinib Aug 20, 2024
<ѻý>Higher Steroid Dose for ICI Toxicity Harms Cancer Survival, Analysis Suggestsѻý> More data for discussion of controversial association between steroids, immunotherapy Aug 19, 2024
<ѻý>FDA Expands Durvalumab Label to Operable Lung Cancerѻý> PD-L1 checkpoint inhibitor approved for use in NSCLC before and after surgery Aug 16, 2024
<ѻý>Cancer Screening Costs Over $43 Billion a Year in the U.S., Study Estimatesѻý> Colorectal cancer screening accounted for 64% of the total amount Aug 05, 2024
<ѻý>FDA Panel Supports More Clarity in NSCLC Perioperative Immunotherapy Trialsѻý> Committee unanimously backs mandating trial design to distinguish effects of therapy phases Jul 25, 2024
<ѻý>Vapers May Be Less Likely to Undergo Lung Cancer Screeningѻý> "Former smokers who use e-cigarettes remain at increased risk of lung cancer," researchers say Jul 02, 2024
<ѻý>Real-World Analysis Identifies Meds Tied to Higher Risk of Liver Injuryѻý> Case reports may not be as reliable, researchers say Jun 25, 2024
<ѻý>Court: Some Employers Can Exclude PrEP, Cancer Screenings From Insurance Coverageѻý> Not all preventive care recommended by the USPSTF is threatened by the narrow ruling, however Jun 24, 2024
<ѻý>Anti-PD-L1 Plus Targeted Agent No Better Than Chemo for Resistant NSCLCѻý> No significant difference between atezolizumab-cabozantinib, docetaxel for OS, PFS, response Jun 20, 2024
<ѻý>Early Menopause Tied to Higher Risk of Respiratory Mortalityѻý> Greatest risk observed for women with bilateral oophorectomy Jun 13, 2024
<ѻý>Another KRAS Inhibitor Scores an Early Win in Advanced Non-Small Cell Lung Cancerѻý> Half of patients responded, but editorialists call for new directions in therapy development Jun 11, 2024
<ѻý>Dendritic Cell Therapy Offers No Survival Advantage in Pleural Mesotheliomaѻý> Immunotherapy may have been given too late, researchers suggested Jun 10, 2024
<ѻý>Lung Cancer Screening Rates Remain Low in the U.S., Especially in the Southѻý> But one study showed that patient navigation added to usual care may increase uptake Jun 10, 2024
<ѻý>Artery Inflammation and CV Events; Stepped Palliative Care for Lung Cancer Patientsѻý> Also in TTHealthWatch: diets and medicine in IBS and active surveillance in prostate cancer Jun 08, 2024 podcast
<ѻý>Limited-Stage SCLC Gets a New Standard of Care With Consolidation Durvalumabѻý> Median OS was 55.9 months in the durvalumab group compared with 33.4 months in the placebo group Jun 03, 2024
<ѻý>'Practice Changing' Trial for Inoperable Locally Advanced NSCLCѻý> EGFR testing now needed for all patients with stage III disease, experts say Jun 02, 2024
<ѻý>Virtual and In-Person Palliative Care Equally Beneficial in Advanced Lung Cancerѻý> No differences observed in quality of life metric, patient and caregiver satisfaction Jun 02, 2024
<ѻý>Subcutaneous Amivantamab Plus Lazertinib Non-Inferior to IV Dosing in NSCLCѻý> Unexpectedly offers a possible overall survival benefit, researchers say Jun 01, 2024
<ѻý>Novel Bispecific in EGFR-Mutant Lung Cancer Boosts PFS After Targeted Agentsѻý> China-based trial may present a hurdle to FDA approval, however Jun 01, 2024
<ѻý>Unprecedented PFS Results in ALK-Positive Lung Cancer Trialѻý> "We have not seen anything close to this," says expert May 31, 2024
<ѻý>Smoking Isn't the Only Source of Nicotine Addiction in Townѻý> Emerging data suggest pharmacological interventions may help patients quit vaping May 29, 2024
<ѻý>Psychostimulant No Help in Relieving Cancer-Related Fatigueѻý> No significant differences in outcomes between methylphenidate, placebo May 22, 2024
<ѻý>FDA OKs Novel BiTE Agent for Small Cell Lung Cancerѻý> First-in-class tarlatamab achieved a 40% ORR in previously treated extensive-stage SCLC May 16, 2024
<ѻý>Perioperative Nivolumab Boosts EFS in Resectable Lung Cancerѻý> CheckMate 77T trial shows 42% reduction in risk of tumor recurrence, progression, or death May 15, 2024
<ѻý>Will AI Replace Radiologists, or Just Make Them Better Than Ever?ѻý> Opinions differ on how much physicians should be embracing the technology May 14, 2024
<ѻý>Glecirasib Shows Promising Efficacy in KRAS-Mutated NSCLCѻý> Trend towards better response rate, PFS compared with approved KRAS inhibitors May 01, 2024
<ѻý>EPA Bans Consumer Use of Toxic Chemical Known to Cause Liver, Lung Cancersѻý> Methylene chloride has killed at least 88 workers since 1980 Apr 30, 2024
<ѻý>White House Indefinitely Delays Plan to Ban Menthol Cigarettesѻý> Biden administration has delayed the final rule several times recently Apr 26, 2024
<ѻý>Alectinib Lands FDA Approval for Adjuvant Therapy in NSCLCѻý> The ALK inhibitor reduced the risk of recurrence or death by 76% versus chemotherapy Apr 19, 2024
<ѻý>Accelerated Aging Linked to Recent Increase in Early-Onset Solid Tumorsѻý> Strength of association increased in more recent birth cohorts Apr 09, 2024