乌鸦传媒

<乌鸦传媒 class='mpt-top_cat_title'>Rheumatology >

Arthritis

News, opinions and meeting coverage in rheumatology.

A man's hand with psoriatic arthritis over a box of Ilumya (tildrakizumab-asmn) for injection.

<乌鸦传媒>Plaque Psoriasis Drug Shows Promise for Psoriatic Arthritis

Monoclonal antibody targets the IL-23 p19 subunit

A Stelara auto injector needle over a grid of close up psoriasis images.

<乌鸦传媒>For Safety, One Biologic a Winner in Psoriasis, Psoriatic Arthritis

Lower hospitalization rates compared with other biologics or small molecule therapies

A Taltz (ixekizumab) auto injector pen over a photo of a mans back, his spine highlighted in red

<乌鸦传媒>Stopping IL-17 Drug for Axial Spondyloarthritis? Expect Spinal Flares

But low disease activity regained if treatment restarted

An illustration of a brain filled with lightbulbs, one is burning brightly, the others are dark.

<乌鸦传媒>The Death of One Little Girl Helped Millions

A case more than 35 years ago has spurred discoveries ever since

An artist rendition of fecal microbiota capsules

<乌鸦传媒>Results Disappoint for Fecal Transplant in Arthritis

But interest persists in targeting the gut-joint axis in psoriatic arthritis

NKF over a computer rendering of kidney disease

<乌鸦传媒>Pegloticase Safe for Dialysis Patients With Gout

Significant drop in monthly ESA dose seen after treatment, too

A Tremfya (guselkumab) syringe with the packaging box over a man's hand with enthesitis and psoriatic arthritis

<乌鸦传媒>For Enthesitis in Psoriatic Arthritis, Target IL-23

Targeted agent provides relief for many PsA patients

A close up of a man鈥檚 hand with psoriatic arthritis over a bottle of Rinvoq (upadacitinib) tablets

<乌鸦传媒>JAK Inhibitor Promising in Psoriatic Arthritis

Oral agent noninferior to adalimumab in joint symptoms

A computer rendering of monoclonal antibodies

<乌鸦传媒>FDA Panel Unhappy With Novel OA Pain Drug

Latest setback for troubled osteoarthritis biologic

The packaging of Taltz (ixekizumab) injection

<乌鸦传媒>Don't Stop Taltz in Psoriatic Arthritis

Significantly more patients relapsed, and more quickly, after withdrawal

A bottle of Rinvoq (upadacitinib) tablets over an x-ray image of a person鈥檚 arthritic hands

<乌鸦传媒>JAK Inhibitor a Hit With RA Patients

Superior to adalimumab on many patient-reported outcomes

A box of Xeljanz (tofacitinib) tablets over a background of thumbs down icons

<乌鸦传媒>JAK Inhibitor Misses Endpoint in Safety Study. Now What?

Major blow to popular class of oral rheumatology drugs

PET scans of a person showing severe vasculitis

<乌鸦传媒>PET Scans Reveal Vascular Inflammation

In giant cell arteritis, imaging confirmed clinical response

A Cosentyx injection pen over a hand with psoriasis

<乌鸦传媒>Spinal Benefits Seen With Cosentyx in PsA

First trial to evaluate response of axial symptoms in psoriatic arthritis to biologic treatment

A close up of a man鈥檚 foot with his big toe swollen from gout

<乌鸦传媒>Lifestyle Mods May Head Off Gout

Four addressable factors appear key

ACR over a computer rendering of a human skeleton with the joints of the fingers highlighted in red

<乌鸦传媒>TYK2 Inhibition Promising in Psoriatic Arthritis

Phase II study found significant benefits for two doses of novel agent

ACR meeting

<乌鸦传媒>COVID Complications Common with Rheumatic Disease

Adverse outcomes included acute kidney injury and congestive heart failure

ACR over a computer rendering of a human skeleton with the joints of the fingers highlighted in red

<乌鸦传媒>Rinvoq for RA: Benefits Persist Beyond 1 Year

Manufacturer's extension study shows no loss of clinical response

A female service member in camouflage fatigues tosses garbage into a burn pit

<乌鸦传媒>Military Burn Pits Linked With RA Seropositivity

Highest risks for anti-CCP antibodies seen for smokers and those with the HLA-DRB1 shared epitope genes

NSAIDs over a pregnant woman holding a white tablet and glass of water above FDA WARNING

<乌鸦传媒>FDA Warns Against NSAIDs in Pregnancy After 20 Weeks

Risk of kidney complications and low amniotic fluids may jeopardize fetus

VS between a package of Orencia (abatacept) and a bottle of Rinvoq (Upadacitinib) over a half yellow and half pink background

<乌鸦传媒>Upadacitinib, Abatacept Go Head to Head in RA

And the winner is... both, depending on whether efficacy or safety is the main criterion

A bearded middle-age man sitting in a chair holding his aching wrist

<乌鸦传媒>Depression and Biologic Use in Arthritis: Chicken or Egg?

Relationship appears to be bi-directional, researchers say

ASIPP over a close up photo of a senior man's pained face with a tear falling

<乌鸦传媒>Capsaicin Injection Improves Knee OA Pain

Investigational treatment targets capsaicin receptor to inactivate local pain fibers

Photo of a woman massaging her arthritic hand and wrist

<乌鸦传媒>Joint Effusion Protective in Hand OA

Unlike synovitis, which was linked with both pain and progression

A photo of Al Roker

<乌鸦传媒>Al Roker's Shoulder Replacement

"Today" co-host and weatherman battles osteoarthritis pain

A bottle of Olumiant (baricitinib) tablets

<乌鸦传媒>Baricitinib and Infections: What's the Risk?

Overall infections increased, but serious infections similar to placebo

The packaging for and a vial of canakinumab (Ilaris)

<乌鸦传媒>IL-1 Blockade: A Treatment at Last for Osteoarthritis?

Canakinumab significantly lowered the risk of joint replacements in exploratory study

A box of Actemra prefilled syringes

<乌鸦传媒>Tocilizumab Raises GI Risks in Rheumatoid Arthritis

Double the risk of one rare but potentially deadly event compared with use of TNF inhibitors, large Swedish study found

A healthcare worker wearing white gloves holds a woman鈥檚 swollen hand

<乌鸦传媒>Targeting IL-23 Relieves Multiple Symptoms in PsA

Both enthesitis and dactylitis improved with guselkumab treatment in psoriatic arthritis

EULAR over a computer rendering of a human body with the major joints glowing red

<乌鸦传媒>Psoriatic Arthritis: Outcomes Similar for Cosentyx and Humira

Primary endpoint of superiority for secukinumab over adalimumab not met in a phase IIIb trial

EULAR over a computer rendering of a human body with the major joints glowing red

<乌鸦传媒>Another IL-6 Blocker Succeeds in Rheumatoid Arthritis

Effective in patients with moderately to severely active disease in a phase III trial

EULAR over a computer rendering of a human body with the major joints glowing red

<乌鸦传媒>EULAR 2020: What to Expect

Cancelled due to pandemic but extensive menu of virtual learning planned

A computer rendering of an antibody

<乌鸦传媒>Biologics Don't Increase Melanoma Risk... Probably

Meta-analysis offers some reassurance, but leaves room for doubt

An x-ray image of a man鈥檚 spine with ankylosing spondylitis

<乌鸦传媒>IL-17A Blockers Succeed in Spine Disease

Secukinumab and ixekizumab best placebo for ankylosing spondylitis

The packaging and syringe for Kineret

<乌鸦传媒>Study Backs Cytokine Targeting for COVID-19 Tx

Interrupting host inflammatory response shows promise

A physician injects a biologic in to a womans arthritic knee

<乌鸦传媒>Rheumatoid Arthritis: Biologic Dose Cuts Feasible

Majority of patients who achieved remission, low disease activity could lower biologic intake without flaring

Boxes of hydroxychloroquine and azithromycin

<乌鸦传媒>HCQ Plus Azithromycin: A Dangerous Combination?

Antimalarial drug appears safe alone; whether it's effective in COVID-19 still unclear

The packaging and prefilled syringe of Tremfya

<乌鸦传媒>Guselkumab a Hit in Phase III for PsA

Primary endpoints met in two large trials in psoriatic arthritis for IL-23 inhibitor

An x-ray image of a spine with ankylosing spondylitis

<乌鸦传媒>IL-17A/F Inhibitor a Winner in Spine Disease

Targeting both cytokines had rapid, sustained benefits in ankylosing spondylitis

X-ray images of the knee and hip, both highlighted in red

<乌鸦传媒>Tanezumab: A Win as Last-Ditch Osteoarthritis Tx

Modest pain reduction seen in patients with no other drug options

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