This study identified specific motor skills as highly sensitive markers of juvenile-onset Huntington鈥檚 disease (JOHD) progression, offering more precise tools for tracking the disease and designing future treatments tailored to patients with JOHD.
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In Huntington鈥檚 Disease, Exploring the Roles of Race, Ethnicity, and Education
A study identified racial and ethnic disparities in Huntington鈥檚 disease, as well as differences based on levels of education of patients, finding that minority patients may be disproportionately affected.
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Neurogenetic Disease Patients and Caregivers May Benefit from End-of-Life Conversations
A French study based on questionnaires and interviews showed a willingness among patients with neurogenetic diseases and their primary caregivers to talk about sensitive issues like advance directives and end-of-life care.
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In Huntington鈥檚 Disease, Depression is Different
Investigators call for psychosocial interventions in those with or at risk for Huntington鈥檚 disease. Taking a personalized approach to address factors such as concern for the future and sleep disturbances is essential.
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In Early-Stage Huntington鈥檚 Disease, Cognitive Trajectories Vary
In a study of adults with early or early-mid Huntington鈥檚 disease, two types of patients emerged: those with a mild, slow progression of cognitive decline and those marked by a more rapid and aggressive decline. How did these groups compare with healthy controls?
An examination of 50 relevant studies found that individuals with any of four major types of hyperkinetic movement disorders consistently exhibited impaired social cognition. What does this mean for them鈥攁nd the professionals who care for them?
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Huntington鈥檚 Disease: A Look at the Global Pace
This updated systematic review and meta-analysis鈥攖he first in at least a decade鈥攁nalyzed rates of this rare inherited neurological disorder in 21 countries, across multiple continents. Have rates gone up, down, or stayed the same?
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In Huntington鈥檚 Disease, How Sleep and Circadian Patterns Affect Cognition
In patients with Huntington鈥檚 disease, poorer sleep is associated with poorer cognitive function. But would these patients benefit from targeted sleep and circadian rhythm modification to improve cognitive function?