乌鸦传媒

Genetics

<乌鸦传媒 class='mpt-top_cat_title_description'>News, opinions and meeting coverage in genetics.

A computer rendering of X and Y chromosomes.

<乌鸦传媒>A Clue on Why Lupus, Other Autoimmune Diseases Strike Far More Women Than Men

New research shows that the extra X chromosome is involved, but in an unexpected way

A photo of a male physician examining the ear of a little boy.

<乌鸦传媒>Novel Gene Therapy Allows Kids With Inherited Deafness to Hear

"This is real proof showing gene therapy is working," says researcher

A photo of a hand holding a well plate in front of an electropherogram

<乌鸦传媒>Cost of Genomic Testing on the Minds of Many Oncologists

Insurance coverage, patient out-of-pocket costs key considerations for 80% of survey respondents

A photo composite designed to resemble a relief of oxen hauling wagons, men, strands of DNA, viruses, and a neuron

<乌鸦传媒>MS Risk Linked to Ancient Migrations

Findings may help demystify multiple sclerosis

A photo of a pregnant woman receiving an ultrasound.

<乌鸦传媒>Retinal Tumor Risk Incidentally Detected at 29 Weeks' Gestation

Finding poses clinical and ethical dilemma for parents and clinicians

FDA APPROVED eplontersen (Wainua) over a computer rendering of amyloidosis

<乌鸦传媒>FDA Approves New Agent for Nerve Pain From Rare Inherited Disease

Eplontersen gets a nod for polyneuropathy from hereditary transthyretin-mediated amyloidosis

ASH over a photo of San Diego Convention Center.

<乌鸦传媒>Pomalidomide Cuts Severe Epistaxis in Genetic Bleeding Disorder

24 weeks of daily treatment significantly reduced recurrent nosebleeds in HHT trial

A computer rendering of a face inhaling a variety of viruses

<乌鸦传媒>Why Is VEXAS Syndrome Often Fatal? Here's an Answer

New study suggests immunodeficiency is a previously unrecognized feature

A computer rendering of DNA editing with CRISPR.

<乌鸦传媒>A Closer Look at the Approval of CRISPR/Cas9 Gene Therapy for Sickle Cell Disease

This landmark event brings up broader considerations and implications for other diseases

A computer rendering of the dorsal striatum and lateral ventricles in the brain of a person with Huntington鈥檚 disease

<乌鸦传媒>Antisense Drug Trial Provides Key Insights About Huntington's Disease

Lessons learned from investigational tominersen

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

<乌鸦传媒>Jamie Foxx's Health Scare; 23andMe Hacked; Decongestant Probe Announced

Health news and commentary from around the Web gathered by 乌鸦传媒 staff

ACAAI over a photo of Anaheim Convention Center in Anaheim, California.

<乌鸦传媒>Here's Why People Think They Developed Food Allergies

Survey finds that 13% thought genetics were responsible, 27% blamed eating behaviors

AHA over a photo of Pennsylvania Convention Center in Philadelphia, Pennsylvania

<乌鸦传媒>Promising Debut for CRISPR Gene Editing Therapy for LDL Lowering

Preliminary data support concept of "molecular surgery" on PCSK9 gene

<乌鸦传媒>Zoonotic Spillovers; DNA and RNA Testing for Cancer Risk

Also in TTHealthWatch: genes and health conditions among Icelanders

FDA APPROVED ADAMTS13, recombinant-krhn (Adzynma) over a computer rendering of a blood clot.

<乌鸦传媒>First Treatment Approved for Genetic Clotting Disorder

Adzynma indicated as prophylactic or on-demand enzyme replacement therapy in cTTP

A photo of a male firefighter standing in front of a fire truck.

<乌鸦传媒>Moving Beyond the 'Angelina Jolie Effect' to Address Cancer Disparities

A "local heroes effect" can better reach communities of color

FDA ADCOMM exagamglogene autotemcel (exa-cel) over a computer rendering of sickle cells in the bloodstream.

<乌鸦传媒>Potential Cure for Sickle Cell Clears Hurdle for Approval

FDA advisors suggest the benefits of gene therapy outweigh risks of off-target editing

A photo of a pipette in a petri dish laying on top of a DNA sequencing gel.

<乌鸦传媒>Quick Genetic Test Offers Hope for Sick, Undiagnosed Kids, but Few Insurers Cover It

Test can "change the trajectory of these children's diseases"

HFSA over a photo of Huntington Convention Center in Cleveland, Ohio.

<乌鸦传媒>FDA Turns Down ATTR Cardiomyopathy Drug

Decision cites insufficient evidence of clinical meaningfulness

A computer rendering of the female reproductive system in the pelvis.

<乌鸦传媒>In BRCA Breast Cancer, Prophylactic Salpingo-Oophorectomy Tied to Better Survival

PSO should be performed early, particularly for those with the BRCA1 variant, researchers say

FDA MARKETING Invitae Common Hereditary Cancers Panel over a photo of the product.

<乌鸦传媒>FDA Greenlights Test for Cancer-Predisposing Genetic Mutations

First-of-its-kind DNA test achieved 99% accuracy for variants in dozens of genes

FDA APPROVED nedosiran (Rivfloza) over a computer rendering of a transparent kidney with kidney stones.

<乌鸦传媒>FDA OKs Another Injectable for Rare Kidney Disorder

Nedosiran approved for patients ages 9 years and older with primary hyperoxaluria type 1

FDA APPROVED cipaglucosidase alfa (Pombiliti) plus miglustat (Opfolda) over a muscle biopsy showing accumulation of glycogen.

<乌鸦传媒>New Option OK'd for Pompe Disease

FDA approves two-component therapy for patients not improving on enzyme replacement therapy

A computer rendering of the dorsal striatum and lateral ventricles in Huntington鈥檚 disease

<乌鸦传媒>Huntington's Disease More Severe in Black Patients at Baseline

Outreach to families of minority patients may help identify genetic disorder

FDA ADCOMM patisiran (Onpattro) over a medical illustration of cardiomyopathy over a microscopy of heart amyloid deposits

<乌鸦传媒>FDA Panel Reluctantly Backs Patisiran for ATTR Cardiomyopathy

Clinical meaningfulness is a different question, however

A photo of a box of Trikafta over CT scans of a male with sinusitis.

<乌鸦传媒>Some Sinus Relief for Cystic Fibrosis Patients on Trikafta

Lung function, BMI, bacterial swabs, sweat chloride levels also improved

A photo of a healthcare worker drawing blood from an infant.

<乌鸦传媒>Rapid Genome Sequencing in Infants With Epilepsy Shows Immediate Benefit

Pilot study suggests early testing for seizures, regardless of treatment setting

FDA APPROVED pozelimab (Veopoz) over a micrograph of the intestinal tissue of a child with CHAPLE disease.

<乌鸦传媒>Ultra-Rare Immune System Disease Gets First FDA-Approved Treatment

Pozelimab reduced hospitalizations, albumin transfusions in CHAPLE disease patients

A close up of a woman鈥檚 eye yellowed by jaundice.

<乌鸦传媒>Gene Therapy Promising for Rare Jaundice Syndrome

Early-phase data suggest a dose that can keep bilirubin in check without hours of phototherapy

Photo of a doctor checking a sports athlete with a stethoscope.

<乌鸦传媒>Cautious Return-to-Play Appears Safe for Athletes With Heart Conditions

Shift away from blanket restrictions is not placing top-tier athletes at undue risk, data suggest

A scanning electron microscope image of a sickle cell.

<乌鸦传媒>New Recommendations Address Global Inequality in Sickle Cell Disease Care

Commission lays out strategies for progress by 2025 and beyond

A graphical representation of a genome sequence map.

<乌鸦传媒>Whole Genome Sequencing Boosts Diagnosis of Rare Disease in Infants

Whole genome scans took longer than a commercially available test, but not for most urgent cases

A computer rendering of damaged nerve cells caused by multiple sclerosis.

<乌鸦传媒>MS Disease Severity Tied to Genetic Variant

Findings mark a significant breakthrough in understanding how MS progresses

FDA ADCOMM palovarotene over a photo of a skeleton of a person who suffered from fibrodysplasia ossificans progressiva

<乌鸦传媒>FDA Staff Weighs 'Alternative' Data on Retinoid for Rare Bone Disorder

Challenges of drug development in fibrodysplasia ossificans progressiva on full display

A computer rendering of aortic dissection.

<乌鸦传媒>Bicuspid Aortic Valves and Aortopathy Cluster Among Close Relatives

Large study supports wider screening of family members of probands

A computer rendering of fat cells.

<乌鸦传媒>High-Dose Leptin Reversed Severe Genetic Obesity in Two Patients

Metreleptin doses several times higher than recommended brought weight down to near normal

A computed tomography angiography of the aorta with stent-grafting in a patient with aortic aneurysm

<乌鸦传媒>Cautious Hope for Endovascular Aortic Tx in Connective Tissue Disease

Success observed in usually contraindicated Marfan, Loeys-Dietz syndromes

A computer rendering of antibodies in the bloodstream.

<乌鸦传媒>Full-On Reversal of Cardiac Amyloidosis Possible With Antibodies

Future treatments don't have to be limited to slowing disease, case series suggests

A photo of a pipette hovering over a petri dish laying on genetic testing results.

<乌鸦传媒>How to Overcome the Catch-22 in Precision Medicine Research

Improving the patient experience will go a long way

FDA APPROVED herpes-simplex virus type 1 vector-based gene therapy (Vyjuvek) over a photo of dystrophic epidermolysis bullosa

<乌鸦传媒>Rare Skin Blistering Condition Gets First Drug Approved

FDA's decision marks first approval for a redosable gene therapy

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