乌鸦传媒

Genetics

<乌鸦传媒 class='mpt-top_cat_title_description'>News, opinions and meeting coverage in genetics.

A close up photo of a fitness tracker on a woman鈥檚 wrist reading 9,606 steps

<乌鸦传媒>Need 10,000 Daily Steps to Prevent Obesity? It May Depend on Genetics

Current recommendations may underestimate activity needs for people with high genetic risk

A photo of a vial of Fluorouracil

<乌鸦传媒>Overdosing on Chemo: A Common Gene Test Could Save Hundreds of Lives Each Year

Treatment can be deadly for enzyme-deficient patients; NCCN doesn't call for preemptive testing

FDA APPROVED ponatinib (Iclusig) over a computer rendering of the destruction of lymphoblast cells

<乌鸦传媒>FDA Approves New Frontline Regimen for Aggressive ALL

Ponatinib lands indication in combination with chemo for Philadelphia chromosome-positive cases

A photo of a physician performing a lumbar puncture

<乌鸦传媒>Spinal Delivery of Gene Therapy Promising for Neurodegenerative Disease

Early-phase clinical trial was suggestive of slower progression of giant axonal neuropathy

A computer rendering of prostate cancer.

<乌鸦传媒>Mutation Linked to Increased Risk of Prostate Cancer Mortality

Cancer-specific mortality twice as high in patients with specific genotype for HSD3B1 allele

A medical illustration of glaucoma.

<乌鸦传媒>Higher Polygenic Risk Score Tied to Increased Risk for Glaucoma

Risk scores may allow action before irreversible damage occurs in those with ocular hypertension

A photo of a female physician talking to her mature female patient in the MRI room.

<乌鸦传媒>Cancer Prevention Strategies Linked to Mortality Reduction in BRCA Carriers

Cohort studies indicate oophorectomy, breast MRI surveillance save lives, researchers say

AAAAI over a photo of Walter E. Washington Convention Center in Washington, DC

<乌鸦传媒>Oral Drug Gains Steam as On-Demand Option for Hereditary Angioedema Attacks

Investigational sebetralstat offered symptom relief in under 2 hours

A photo of Joni Rutter, PhD

<乌鸦传媒>Faster Cures, More Genetic Treatments: A Q&A With NIH's Joni Rutter

The NCATS Biomedical Data Translator is giving researchers ideas for new disease therapies

A computer rendering of a transparent body with the appendix highlighted

<乌鸦传媒>Potential Biomarker for Perforated Appendicitis Shows Link to Severe Sepsis

Test that can differentiate between simple and perforated appendicitis is "highly desirable"

SMFM over a photo of Gaylord National Resort & Convention Center in National Harbor, MD

<乌鸦传媒>Genome Sequencing Identified Variants in Fetal Structural Anomalies

Researcher touts identification of "high percentage of genetic disorders"

A photo of a woman receiving an ultrasound early in her pregnancy.

<乌鸦传媒>More Patients Rely on Early Prenatal Testing as States Toughen Abortion Laws

But testing early in pregnancy may be inaccurate

A computer rendering of X and Y chromosomes.

<乌鸦传媒>A Clue on Why Lupus, Other Autoimmune Diseases Strike Far More Women Than Men

New research shows that the extra X chromosome is involved, but in an unexpected way

A photo of a male physician examining the ear of a little boy.

<乌鸦传媒>Novel Gene Therapy Allows Kids With Inherited Deafness to Hear

"This is real proof showing gene therapy is working," says researcher

A photo of a hand holding a well plate in front of an electropherogram

<乌鸦传媒>Cost of Genomic Testing on the Minds of Many Oncologists

Insurance coverage, patient out-of-pocket costs key considerations for 80% of survey respondents

A photo composite designed to resemble a relief of oxen hauling wagons, men, strands of DNA, viruses, and a neuron

<乌鸦传媒>MS Risk Linked to Ancient Migrations

Findings may help demystify multiple sclerosis

A photo of a pregnant woman receiving an ultrasound.

<乌鸦传媒>Retinal Tumor Risk Incidentally Detected at 29 Weeks' Gestation

Finding poses clinical and ethical dilemma for parents and clinicians

FDA APPROVED eplontersen (Wainua) over a computer rendering of amyloidosis

<乌鸦传媒>FDA Approves New Agent for Nerve Pain From Rare Inherited Disease

Eplontersen gets a nod for polyneuropathy from hereditary transthyretin-mediated amyloidosis

ASH over a photo of San Diego Convention Center.

<乌鸦传媒>Pomalidomide Cuts Severe Epistaxis in Genetic Bleeding Disorder

24 weeks of daily treatment significantly reduced recurrent nosebleeds in HHT trial

A computer rendering of a face inhaling a variety of viruses

<乌鸦传媒>Why Is VEXAS Syndrome Often Fatal? Here's an Answer

New study suggests immunodeficiency is a previously unrecognized feature

A computer rendering of DNA editing with CRISPR.

<乌鸦传媒>A Closer Look at the Approval of CRISPR/Cas9 Gene Therapy for Sickle Cell Disease

This landmark event brings up broader considerations and implications for other diseases

A computer rendering of the dorsal striatum and lateral ventricles in the brain of a person with Huntington鈥檚 disease

<乌鸦传媒>Antisense Drug Trial Provides Key Insights About Huntington's Disease

Lessons learned from investigational tominersen

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

<乌鸦传媒>Jamie Foxx's Health Scare; 23andMe Hacked; Decongestant Probe Announced

Health news and commentary from around the Web gathered by 乌鸦传媒 staff

ACAAI over a photo of Anaheim Convention Center in Anaheim, California.

<乌鸦传媒>Here's Why People Think They Developed Food Allergies

Survey finds that 13% thought genetics were responsible, 27% blamed eating behaviors

AHA over a photo of Pennsylvania Convention Center in Philadelphia, Pennsylvania

<乌鸦传媒>Promising Debut for CRISPR Gene Editing Therapy for LDL Lowering

Preliminary data support concept of "molecular surgery" on PCSK9 gene

<乌鸦传媒>Zoonotic Spillovers; DNA and RNA Testing for Cancer Risk

Also in TTHealthWatch: genes and health conditions among Icelanders

FDA APPROVED ADAMTS13, recombinant-krhn (Adzynma) over a computer rendering of a blood clot.

<乌鸦传媒>First Treatment Approved for Genetic Clotting Disorder

Adzynma indicated as prophylactic or on-demand enzyme replacement therapy in cTTP

A photo of a male firefighter standing in front of a fire truck.

<乌鸦传媒>Moving Beyond the 'Angelina Jolie Effect' to Address Cancer Disparities

A "local heroes effect" can better reach communities of color

FDA ADCOMM exagamglogene autotemcel (exa-cel) over a computer rendering of sickle cells in the bloodstream.

<乌鸦传媒>Potential Cure for Sickle Cell Clears Hurdle for Approval

FDA advisors suggest the benefits of gene therapy outweigh risks of off-target editing

A photo of a pipette in a petri dish laying on top of a DNA sequencing gel.

<乌鸦传媒>Quick Genetic Test Offers Hope for Sick, Undiagnosed Kids, but Few Insurers Cover It

Test can "change the trajectory of these children's diseases"

HFSA over a photo of Huntington Convention Center in Cleveland, Ohio.

<乌鸦传媒>FDA Turns Down ATTR Cardiomyopathy Drug

Decision cites insufficient evidence of clinical meaningfulness

A computer rendering of the female reproductive system in the pelvis.

<乌鸦传媒>In BRCA Breast Cancer, Prophylactic Salpingo-Oophorectomy Tied to Better Survival

PSO should be performed early, particularly for those with the BRCA1 variant, researchers say

FDA MARKETING Invitae Common Hereditary Cancers Panel over a photo of the product.

<乌鸦传媒>FDA Greenlights Test for Cancer-Predisposing Genetic Mutations

First-of-its-kind DNA test achieved 99% accuracy for variants in dozens of genes

FDA APPROVED nedosiran (Rivfloza) over a computer rendering of a transparent kidney with kidney stones.

<乌鸦传媒>FDA OKs Another Injectable for Rare Kidney Disorder

Nedosiran approved for patients ages 9 years and older with primary hyperoxaluria type 1

FDA APPROVED cipaglucosidase alfa (Pombiliti) plus miglustat (Opfolda) over a muscle biopsy showing accumulation of glycogen.

<乌鸦传媒>New Option OK'd for Pompe Disease

FDA approves two-component therapy for patients not improving on enzyme replacement therapy

A computer rendering of the dorsal striatum and lateral ventricles in Huntington鈥檚 disease

<乌鸦传媒>Huntington's Disease More Severe in Black Patients at Baseline

Outreach to families of minority patients may help identify genetic disorder

FDA ADCOMM patisiran (Onpattro) over a medical illustration of cardiomyopathy over a microscopy of heart amyloid deposits

<乌鸦传媒>FDA Panel Reluctantly Backs Patisiran for ATTR Cardiomyopathy

Clinical meaningfulness is a different question, however

A photo of a box of Trikafta over CT scans of a male with sinusitis.

<乌鸦传媒>Some Sinus Relief for Cystic Fibrosis Patients on Trikafta

Lung function, BMI, bacterial swabs, sweat chloride levels also improved

A photo of a healthcare worker drawing blood from an infant.

<乌鸦传媒>Rapid Genome Sequencing in Infants With Epilepsy Shows Immediate Benefit

Pilot study suggests early testing for seizures, regardless of treatment setting

FDA APPROVED pozelimab (Veopoz) over a micrograph of the intestinal tissue of a child with CHAPLE disease.

<乌鸦传媒>Ultra-Rare Immune System Disease Gets First FDA-Approved Treatment

Pozelimab reduced hospitalizations, albumin transfusions in CHAPLE disease patients

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