乌鸦传媒

Genetics

<乌鸦传媒 class='mpt-top_cat_title_description'>News, opinions and meeting coverage in genetics.

A close up of a Black woman with a pink breast cancer ribbon pinned to her tank top

<乌鸦传媒>Oncotype DX Misses on Breast Cancer Risk in Black Women

Accuracy of 21-gene recurrence score worse compared with white women

A computer rendering of pink DNA strands

<乌鸦传媒>Not Just BRCA: Large Studies ID Other Key Breast Cancer Risk Genes

Implications for screening and other risk-management strategies, researchers say

Bottles of Lynparza (olaparib) tablets 150 mg and 100 mg

<乌鸦传媒>Broader Role for PARP Inhibitors in Breast Cancer?

Responses in tumors with somatic or germline mutations related to HRD

SABCS over a photo of women holding pink breast cancer ribbons

<乌鸦传媒>Online Tool Refines Individual Risks in Breast Cancer

RSClin incorporates 21-gene recurrence score with tumor grade, size, and more

ASH over a computer rendering of blood flowing through an artery

<乌鸦传媒>Gene Therapy Stops Bleeding in Hemophilia

Single injection had durable effectiveness, study showed

AHA over a computer rendering of a human heart

<乌鸦传媒>ANGPTL3 Blocker Halves LDL in High-Risk Group

Evinacumab worked in patients refractory to statins, PCSK9 inhibitors

The African continent divided up by the country flags next to a young Black male

<乌鸦传媒>SPRINT: African Ancestry Not an Innate CVD Risk in Blacks

Study refutes genetic basis for racial disparities in hypertension, CVD

An obese male child holds his belly

<乌鸦传媒>MC4 Agonist Cuts Body Weight, Hunger in Genetically-Driven Obesity

Trial success raises questions about broader application

A female service member in camouflage fatigues tosses garbage into a burn pit

<乌鸦传媒>Military Burn Pits Linked With RA Seropositivity

Highest risks for anti-CCP antibodies seen for smokers and those with the HLA-DRB1 shared epitope genes

A photo of a one month supply of Hormone Replacement Therapy pills in a blister pack.

<乌鸦传媒>Which Women Choose Hormones for Surgical Menopause?

Understanding patterns of use can help improve targeting for education and counseling, researchers say

Brain scan images with NeuroBreak in the center.

<乌鸦传媒>Dementia Tied to Olfaction; Preclinical Alzheimer's Trial; Guillain-Barr茅 and COVID-19

News and commentary from the world of neurology and neuroscience

IAC Over a photo of an aids ribbon

<乌鸦传媒>HIV: Don't Quit on Hope, Says 'London Patient'

IAC roundtable addresses prospects for cure, now proven to be possible

AACR over a computer rendering of a tumor

<乌鸦传媒>Talzenna Misses OS Endpoint in BRCA-Positive Breast Cancer

But PARP inhibitor improved patient-reported outcomes over standard therapy

A blue gloved hand holds a test tube labeled G6PD with the negative box checked

<乌鸦传媒>Does G6PD Deficiency Relate to COVID-19 Infection?

Several hints of one, pointing to need for focused research

ACC over a computer rendering of the human heart

<乌鸦传媒>Mavacamten Promising in Non-Obstructive HCM

Phase II MAVERICK-HCM trial looked at safety, efficacy of myosin inhibitor

ACC over a computer rendering of the human heart

<乌鸦传媒>Homozygous FH Falls to Praluent, Novel Agent

Drugs succeed in cutting LDL in extra-refractory form of high cholesterol

Petri dishes containing red liquid and DNA sequencing

<乌鸦传媒>SCOTUS Punts on Biomarker Test Patents

Wide-ranging issue effectively referred to Congress

<乌鸦传媒>IGHV-Unmutated CLL: Gene Signature May Predict Outcomes After First-Line FCR

Prognostic tool may predict who is likely to achieve a relatively long remission

A newborn baby facing away from the camera sleeping

<乌鸦传媒>Deaf Parents Want Deaf Baby: Bioethicist Weighs In

You voted, now see the results and an expert's discussion

A photo of Mila and Julia Vitarello

<乌鸦传媒>Mila's N-of-1 Trial Detailed in NEJM

Neurologic scores stabilized, seizures diminished with tailored antisense oligonucleotide therapy

Fludarabine, cyclophosphamide, and rituximab over a chronic lymphocytic leukemia (CLL) blood smear under light microscopy

<乌鸦传媒>FCR Still an Option in IGHV-Unmutated CLL?

Gene signature identifies lower-risk group with greater chemoimmunotherapy benefit

A digital collage of a human fetus and DNA helix

<乌鸦传媒>Ethics Consult: Deaf Couple Only Wants Deaf Baby

You make the call: should doctor implant embryo selected for deafness?

A view inside the human eye showing the retina, optic nerve, and macula

<乌鸦传媒>Faulty Amino Acid Metabolism Linked to Rare Eye Disease

Study helps explain genetic heterogeneity in macular telangiectasia type 2

Photo of John Elway throwing a football

<乌鸦传媒>John Elway鈥檚 Debilitating Hand Condition

Hall of Famer fights Dupuytren's contracture

An illustration of two gloved hands with tweezers removing pieces of a DNA strand

<乌鸦传媒>Good News, Bad News for CRISPR Gene Editing for HIV Cure

"Bigger story for the gene-editing field than the HIV field"

WCLC over a photo of Gran Via, Fira de Barcelona

<乌鸦传媒>'Dirtier' Drugs Step Aside in RET-Positive NSCLC

Over two-thirds of patients respond to selective RET inhibitor

Photo of Henry T. Lynch, MD, PhD

<乌鸦传媒>The Legacy of Henry Lynch, MD

Earlier this summer the legendary researcher passed, his contributions to cancer research are immeasurable

n-of-1 over a photo of a gloved hand plucking a piece from a DNA strand with tweezers

<乌鸦传媒>Desperate Families Pursue 'N-of-1' Trials for Ultra-Rare Diseases

Technology dangles hope of cure -- for those able to pay

LDL particles binding to LDL receptors on the cell membrane

<乌鸦传媒>The Alzheimer's-Cholesterol Connection

Parallel lines of evidence link the two in early-onset Alzheimer's disease

<乌鸦传媒>Fertility Fraud; Pharma's 'Patient' Advocacy; Mass. Nursing Homes Fined

This past week in healthcare investigations

<乌鸦传媒>Bespoke Babies to Prevent CF: Best Use Case or Ethical Bog?

Bioethicist and pediatrician debate cystic fibrosis gene-editing

<乌鸦传媒>Genetic Profiling Disappoints for CUP Survival

But testing in cancer of unknown primary site did help with prognosis

<乌鸦传媒>Parkinson's Gene Therapy Shows Signs of Motor Improvement

Early open-label trial in advancing Parkinson's disease showed treatment was safe, well-tolerated

<乌鸦传媒>Cannabis Use Again Tied to Risk for Psychotic-Like Experiences

Genetics underlies the association, but heavy use may also play a role

<乌鸦传媒>Mysteries Solved at NIH Program for Undiagnosed Illnesses

Dx has come to light in 35% of accepted cases so far

<乌鸦传媒>Inherited JAK3 Mutation May Up Head/Neck Ca Risk in African Americans

About 8% carry the single nucleotide polymorphism

<乌鸦传媒>Frequent Basal Cell Cancers Sign of Broader Inherited Risk

Tripled rates of internal malignancies such as breast and prostate tumors

<乌鸦传媒>Afib Patch Test; Heart Failure and Genetics: It's PodMed Double T!

This week's topics include a patch to diagnose atrial fibrillation, USPSTF recommendations on nontraditional risk factors for heart disease, the role of genetics in congestive heart failure, and multivitamins and heart disease.

<乌鸦传媒>Genetic Role in Heart Failure Seen in Adoption Study

Researchers suggest searching for specific variants

<乌鸦传媒>ADHD Higher in Preterm Babies, Especially Girls

Sibling study shows association may not be tied to genes or family environment

5