AAD
<ѻý class="page-description">American Academy of Dermatologyѻý>High response rates out to 52 weeks with IL-23 inhibitor, correlating with eradication of T cells
Itch, sleep disturbance, lesion healing, quality of life improved substantially in most patients
Noninferiority achieved across all skin subtypes
At least 50% reduction in abscess, nodule count at 16 weeks for more than 70% of patients
Almost 40% of patients had no more than one active lesion after 12 weeks of berdazimer gel
Rapid reduction in itch, sleep disturbance, nodules after first dose of nemolizumab
Responses often maintained after drug withdrawal, long-term persistence with ongoing treatment
Rates of 90% clearance approaching 50% at 12 weeks, with 100% clearance rates as high as 33%
Disease status, itch improved significantly within 1 to 2 weeks with roflumilast cream
New analyses show "unprecedented" rates of 50% to 100% improvement
About 40% of patients go from nearly hairless to almost a full head of hair with deuruxolitinib
"Dramatic improvement" at 16 weeks with IL-23 blocker after lack of response to anti-IL-17 drug
AAD data also promising for therapies in psoriasis, pyoderma gangrenosum
No reduction in vascular inflammation with apremilast but significant reduction in body fat
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AAD: American Academy of Dermatology
March 2024
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ISDS: Inflammatory Skin Disease Summit
November 2021
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EADV: European Academy of Dermatology and Venereology
October 2020
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SID: Society for Investigative Dermatology
May 2020